Recombinant Human Ferritin Heavy Chain/FTH Protein

• Catalog number
  PKSH032423-10µg
• Price
  Please ask
• Size
  10µg

• Synonym
  Ferritin heavy chain;FTH1;FTH;FTHL6;Ferritin H subunit;Cell proliferation-inducing gene 15 protein
• Activity
  NA
• Sequence
  Met1-Ser183
• Fusion tag
  NA
• Accession
  P02794
• Expressed Host
  E.coli
• Shipping
  The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
• Purity
  ＞95% as determined by reducing SDS-PAGE.
• Endotoxin
  ＜1.0 EU per µg as determined by LAL test.
• Stability and Storage
  Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months
• Mol Mass
  21.2 kDa
• AP Mol Mass
  22 kDa
• Formulation
  Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
• Background
  Ferritin heavy polypeptide 1(FTH1), is a ubiquitous intracellular protein which stores iron in a soluble, non-toxic, readily available form. FTH1 has ferroxidase activity and is important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Ferritin is composed of 24 subunits of the light and heavy ferritin chains. It plays a role in delivery of iron to cells and mediates iron uptake in capsule cells of the developing kidney. Variation of ferritin subunit composition may affect iron absorption and release in different tissues. Deficiency of ferritin proteins may cause several neurodegenerative diseases. Almost all living organisms can produce this protein, including algae, bacteria, higher plants, and animals.
• Technical data
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Ferritin   Heavy   Chain/FTH   Protein  
• Gene symbol
  FTH1
• Short name
  Recombinant Ferritin Heavy Chain/FTH Protein
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens Ferritin Heavy epitope/FTH Protein
• Alternative technique
  rec

Gene info

• Identity
  HGNC:3976
• Gene
  FTH1
• Long gene name
  ferritin heavy chain 1
• Synonyms gene
  • FTHL6
• Synonyms gene name
  • ferritin, heavy polypeptide 1
• Synonyms
  • FTH
  • PLIF
  • PIG15
  • FHC
• Synonyms name
  • apoferritin
  • placenta immunoregulatory factor
  • proliferation-inducing protein 15
• Locus
  11q12.3
• Discovery year
  2001-06-22
• Entrez gene record
  2495
• Pubmed identfication
  • 3020541
• RefSeq identity
  • NM_002032
• Classification
  • Ferritin subunits
• VEGA ID
  OTTHUMG00000166217

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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