FH535

• Catalog number
  2657-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  2,5-Dichloro-N-(2-methyl-4-nitrophenyl)benzenesulfonamide
• Description
  FH535 is a potent, reversible dual inhibitor of Wnt/β-catenin and a PPARγ and PPARδ signaling. FH535 antagonizes both PPARg and PPARδ ligand-dependent activation and shows structural similarity to GW9662, a known PPARgamma antagonist. The compound is selectively toxic to some carcinomas expressing the Wnt/β-catenin pathway.
• CAS Number
  108409-83-2
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₃H₁₀Cl₂N₂O₄S
• Molecular Weight
  361.2
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (~25 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A Wnt pathway antagonist
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• MDL Number
  MFCD01212888
• PubChem CID
  3463933
• PubChem CID Link
• SMILES
  CC1=C(C=CC(=C1)[N+](=O)[O-])NS(=O)(=O)C2=C(C=CC(=C2)Cl)Cl
• InChi
  InChI=1S/C13H10Cl2N2O4S/c1-8-6-10(17(18)19)3-5-12(8)16-22(20,21)13-7-9(14)2-4-11(13)15/h2-7,16H,1H3
• InChi Key
  AXNUEXXEQGQWPA-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  FH535  
• Short name
  FH535
• Alternative name
  FH535

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