Nimesulide is a selective cyclooxygenase-2 (COX-2) inhibitor. The IC₅₀ values are 70 and 1.27 µM for human recombinant COX-1 and -2 (at 20 µM arachidonic acid), respectively, and 22 and 0.03 µM for ovine COX-1 and -2 (at 100 µM arachidonic acid), respectively.
Is it cell-permeable?
Is this a salt?
Protect from air and light
Maximum time for storage
DMSO (~30 mg/ml) or EtOH (~ 7 mg/ml)
For cells, cell lines and tissues in culture till half confluency.