anti- TGF-beta 3 antibody
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Catalog numberFNab08640
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PricePlease ask
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Size2X100μg
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Formliquid
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PurificationImmunogen affinity purified
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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BackgroundThis gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. This protein is involved in embryogenesis and cell differentiation, and may play a role in wound healing. Mutations in this gene are a cause of aortic aneurysms and dissections, as well as familial arrhythmogenic right ventricular dysplasia 1.
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Immunogentransforming growth factor, beta 3
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SynonymsARVD;ARVD1;LDS5;RNHF;TGF-beta3
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Calculated MW45KD
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Uniprot IDP10600
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SpecificityHuman, Mouse, Rat
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Tested ApplicationELISA, WB, IHC
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Recommended dilutionWB: 1:500 - 1:2000; IHC: 1:50 - 1:100
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Image1Immunohistochemistry of paraffin-embedded mouse ovary using FNab08640(TGFB3 antibody) at dilution of 1:100
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Image4K-937 cells were subjected to SDS PAGE followed by western blot with FNab08640(TGFB3 antibody) at dilution of 1:1000
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
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PropertiesIf you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolTAB3, TAB3P1, CSRNP3
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Short nameanti- TGF-beta 3 antibody
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TechniqueAntibody, anti, antibody to, antibodies against human proteins, antibodies for
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HostRabbit
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IsotypeIgG
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Alternative nameantibody to- TGF-b 3 (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameTGF-beta activated kinase 1 (MAP3K7) binding protein 3
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Synonyms gene
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Synonyms gene name
- mitogen-activated protein kinase kinase kinase 7 interacting protein 3
- TGF-beta activated kinase 1/MAP3K7 binding protein 3
- TGF-beta activated kinase 1 and MAP3K7 binding protein 3
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Synonyms name
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GenBank acession
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Locus
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Discovery year2006-06-26
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Zinc fingers RANBP2-type
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameTGF-beta activated kinase 1/MAP3K7 binding protein 3 pseudogene 1
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Locus
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Discovery year2010-02-05
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Entrez gene record
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecysteine and serine rich nuclear protein 3
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Synonyms gene
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Synonyms gene name
- family with sequence similarity 130, member A2
- cysteine-serine-rich nuclear protein 3
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2007-01-19
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Protein phosphatase 1 regulatory subunits
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data