anti-IL-25 Antibody [68C1039.2]

• Catalog number
  48-560
• Price
  Please ask
• Size
  0.05 mg

• Gene info
  Recently, a number of cytokines belonging to the interleukin (IL)-17 family have been identified. These are termed as IL-17B, IL-17C and IL-17E. IL-17 is a potent proinflammatory cytokine that plays roles in a number of diseases including rheumatoid arthritis , multiple sclerosis , and promotion of tumor growth. IL-17B, C, and E like IL-17 are able to induce proinflammatory responses. However, they do not bind to the IL-17 receptor suggesting that additional IL-17R related receptor might exist. Receptor for IL-17B and IL-17E has been independently isolated by Shi, et al and Lee, et al. and has been designated as EV127 (in mouse) and IL-17Rh1 (in human), respectively. IL-17E induces activation of NF-kB pathway and like IL-17 also induces production of IL-8. The IL17 proteins are a family of potent cytokines that act to induce proinflammatory responses. Studies have shown that IL17E binds strongly to IL17RB. Receptor binding of ligand has been shown to lead to the activation of nuclear factor kappa-B and production of IL8. Exposure of mice to IL17 resulted in a Th-2 like response characterized by increased serum IgE, IgG1 and IgA levels, blood eosinophilia, increased lymphocytes and neutrophils, and pathological changes in the tissues that included eosinophilic infiltrates, increased mucus production, B-lymphocyte hyperplasia and epithelial cell hyperplasia/hypertrophy.
• Gene names
  IL25, Interleukin 17E, Interleukin 25, Interleukin-25, IL17E, IL-17E, IL-25, Interleukin-17E
• Antibodie s label
  unlabelled serum
• Purity
  Protein G Column
• Ab raised in
  Mouse
• Type
  Monoclonal
• Monoclonal
  [68C1039.2]
• Immunoglobulin
  IgG1
• Antigen
  IL - 25 monoclonal antibody was made against amino acids 115 - 132 of IL - 25 (Human).
• Immuno application
  Western Blot, immuno-histo-chemistry
• Antibody advice
  IL-25 antibody can be used in ELISA starting at 1: 10000, Western Blot starting at 1: 500 - 1: 2000, and immunohistochemistry starting at 1:200.
• Suspention pH azide
  PBS, 0.05% sodium azide
• Keep at
  IL-25 antibody should be stored long term (months) at -20 grades C and short term (weeks) at 4 grades C. As with all antibodies avoid freeze/thaw cycles.
• Works with
  Human, Mouse
• Omim nr
  20138730
• Ncbi nr
  Q9H293
• Vial with antibody
  in solution
• NCBI GENE nr
  64806
• GENE symbol
  IL25
• Antigene name
  interleukin 25
• Source
  Homo sapiens
• Protein nr
  Q9H293
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  IL-25   [68C1039  
• Gene symbol
  IL25, MYDGF, SNORD116-25, ZNF211, SNORD114-25, SNORD115-25, ERVW-25, IGKV3D-25, RNVU1-25, IGLV3-25
• Short name
  anti-IL-25 Antibody [68C1039 2]
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toIL-25 (antibody to-) [68C1039.2]
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:13765
• Gene
  IL25
• Long gene name
  interleukin 25
• Synonyms gene
  • IL17E
• Synonyms gene name
  • interleukin 17E
• Synonyms
  • IL-25
  • IL-17E
• GenBank acession
  • AF305200
• Locus
  14q11.2
• Discovery year
  2001-01-26
• Pubmed identfication
  • 11058597
  • 11754819
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000028749

Gene info

• Identity
  HGNC:16948
• Gene
  MYDGF
• Long gene name
  myeloid derived growth factor
• Synonyms gene
  • IL27
  • IL27w
  • C19orf10
• Synonyms gene name
  • interleukin 27 working designation
  • chromosome 19 open reading frame 10
• Synonyms
  • R33729_1
  • IL25
  • SF20
  • IL-25
  • IL-27
• GenBank acession
  • AF282264
• Locus
  19p13.3
• Discovery year
  2002-04-03
• Entrez gene record
  56005
• Pubmed identfication
  • 17362502
  • 21128247
  • 25581518
• RefSeq identity
  • NM_019107
• VEGA ID
  OTTHUMG00000182039

Gene info

• Identity
  HGNC:33091
• Gene
  SNORD116-25
• Long gene name
  small nucleolar RNA, C/D box 116-25
• Synonyms
  • HBII-85-25
• GenBank acession
  • AF250841
• Locus
  15q11.2
• Discovery year
  2007-02-15
• Entrez gene record
  100033436
• Pubmed identfication
  • 11106375
  • 11726556
• RefSeq identity
  • NR_003339
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:13003
• Gene
  ZNF211
• Long gene name
  zinc finger protein 211
• Synonyms
  • ZNF-25
  • CH2H2-25
• GenBank acession
  • U38904
• Locus
  19q13.4
• Discovery year
  1999-09-29
• Pubmed identfication
  • 7633419
  • 9096115
• Classification
  • Zinc fingers C2H2-type
• VEGA ID
  OTTHUMG00000168012

Gene info

• Identity
  HGNC:33013
• Gene
  SNORD114-25
• Long gene name
  small nucleolar RNA, C/D box 114-25
• Synonyms
  • 14q(II-25)
• Locus
  14q32.31
• Discovery year
  2006-09-26
• Entrez gene record
  767605
• Pubmed identfication
  • 12045206
• RefSeq identity
  • NR_003218.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:33044
• Gene
  SNORD115-25
• Long gene name
  small nucleolar RNA, C/D box 115-25
• Synonyms
  • HBII-52-25
• GenBank acession
  • AF250841
• Locus
  15q11.2
• Discovery year
  2007-02-15
• Entrez gene record
  100033801
• Pubmed identfication
  • 11106375
  • 11726556
• RefSeq identity
  • NR_003342.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:49313
• Gene
  ERVW-25
• Long gene name
  endogenous retrovirus group W member 25
• Synonyms gene name
  • endogenous retrovirus group W, member 25
• GenBank acession
  • HG421063
• Locus
  13q13.3
• Discovery year
  2013-10-21

Gene info

• Identity
  HGNC:5826
• Gene
  IGKV3D-25
• Long gene name
  immunoglobulin kappa variable 3D-25 (pseudogene)
• Synonyms gene name
  • immunoglobulin kappa variable 3D-25
  • immunoglobulin kappa variable 3D-25 pseudogene
• GenBank acession
  • X71886
• Locus
  2p11.2
• Discovery year
  2000-04-18
• Entrez gene record
  28873
• RefSeq identity
  • NG_000833
• Classification
  • Immunoglobulin kappa locus at 2p11.2
• VEGA ID
  OTTHUMG00000151609

Gene info

• Identity
  HGNC:54428
• Gene
  RNVU1-25
• Long gene name
  RNA, variant U1 small nuclear 25
• Locus
  1q21.1
• Discovery year
  2019-07-26
• Classification
  • Variant U1 small nuclear RNAs

Gene info

• Identity
  HGNC:5908
• Gene
  IGLV3-25
• Long gene name
  immunoglobulin lambda variable 3-25
• GenBank acession
  • X97474
• Locus
  22q11.22
• Discovery year
  2000-05-08
• Entrez gene record
  28793
• RefSeq identity
  • NG_000002
• Classification
  • Immunoglobulin lambda locus at 22q11.2
• VEGA ID
  OTTHUMG00000151221

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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