Trovafloxacin mesylate

  • Catalog number
    B1565-5
  • Price
    Please ask
  • Size
    5 mg
  • Alternative_name
    7-[(1α,5α,6α)-6-Amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid mesylate; CP 99219
  • Description
    Trovafloxacin is a broad-spectrum fluoroquinolone antibiotic that inhibits the uncoiling of supercoiled DNA in bacteria by blocking the activity of topoisomerase IV (IC₅₀ = 3.02 µg/ml) and DNA gyrase (IC₅₀ = 7.13 µg/ml). Displays potent activity against gram-positive and gram-negative bacteria.
  • CAS Number
    147059-75-4
  • Molecular Formula
    C₂₀H₁₅F₃N₄O₃.CH₃SO₃H
  • Molecular Weight
    512.46
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO (40 mg/ml) or H₂O (>20 mg/ml)
  • Handling
    Protect from air and moisture
  • Tag Line
    A broad-spectrum fluoroquinolone antibiotic
  • Storage Condition
    -20°C
  • Shipping Condition
    Gel Pack
  • Shelf Life
    36 months
  • MDL Number
    MFCD00913361
  • PubChem CID
    62960
  • SMILES
    CS(=O)(=O)O.C1C2C(C2N)CN1C3=C(C=C4C(=O)C(=CN(C4=N3)C5=C(C=C(C=C5)F)F)C(=O)O)F
  • InChi
    InChI=1S/C20H15F3N4O3.CH4O3S/c21-8-1-2-15(13(22)3-8)27-7-12(20(29)30)17(28)9-4-14(23)19(25-18(9)27)26-5-10-11(6-26)16(10)24;1-5(2,3)4/h1-4,7,10-11,16H,5-6,24H2,(H,29,30);1H3,(H,2,3,4)/t10-,11+,16?;
  • InChi Key
    DYNZICQDCVYXFW-GIPYJWDTSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    Trovafloxacin mesylate
  • Alternative name
    Trovafloxacin mesylate
MeSH Data
  • Name
  • Concept
    Scope note: The insertion of recombinant DNA molecules from prokaryotic and/or eukaryotic sources into a replicating vehicle, such as a plasmid or virus vector, and the introduction of the resultant hybrid molecules into recipient cells without altering the viability of those cells.
  • Tree numbers
    • E05.393.220
  • Qualifiers
    drug effects, methods, radiation effects
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