Recombinant Human HSP27 / HSPB1 Protein (His tag) 100µg
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Catalog number
PKSH031656-100µg
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Price
Please ask
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Size
100µg
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Synonym
CMT2F;HEL-S-102;HMN2B;HS.76067;Hsp25;HSP27;HSP28;SRP27
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Activity
NA
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Sequence
Met1-Lys205
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Fusion tag
C-His
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Accession
NP_001532.1
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Expressed Host
E. coli
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Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
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Purity
> 97 % as determined by SDS-PAGE
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Endotoxin
Please contact us for more information.
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Stability and Storage
Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Mol Mass
28 kDa
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AP Mol Mass
28 kDa
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Formulation
Lyophilized from sterile 20mM HEPES, 0.1M KCl, pH 7.5
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Reconstitution
Please refer to it for detailed information.
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Background
Granzyme B, also known as GZMB, is the most prominent member of the granzyme family of cell death-inducing serine proteases expressed in the granules of cytotoxic T lymphocytes (CTLs) and NK cells. Granzyme B enters the target cells depending on another membrane-binding granule protein, perforin, results in the activation of effector caspases and mitochondrial depolarization through caspase-dependent and -independent pathways, and consequently induces rapid cell apoptosis. Over 30 substrates of GZMB have been identified including the key substrate caspase-3, ICAD and Bid. GZMB is suggested to protect the host by lysing cells bearing on their surface 'nonself' antigens such as bacterial and viral infected-cells and tumor cells, and accordingly plays an essential role in immunosurveillance.
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Conjugation
histidine
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
HSPB1
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Short name
Recombinant HSP27 / HSPB1 Protein (His tag) 100µg
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
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Label
His
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Species
Human, Humans
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Alternative name
Rec. H. sapiens HSP27 / heat shock 27kDa protein 1 Protein (histidine detection labelled) 100µg
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Alternative technique
rec
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Alternative to gene target
heat shock 27kDa protein 1, CMT2F and HEL-S-102 and HMN2B and HS.76067 and Hsp25 and HSP27 and HSP28 and SRP27, HSPB1 and IDBG-23058 and ENSG00000106211 and 3315, poly(A) RNA binding, nuclei, Hspb1 and IDBG-204151 and ENSMUSG00000004951 and 15507, HSPB1 and IDBG-640144 and ENSBTAG00000011969 and 516099
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Gene info
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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