Human CellExp™ B7-H5 / VISTA, Human recombinant

• Catalog number
  9242-50
• Price
  Please ask
• Size
  50 µg

• Synonyms
  B7-H5, SISP1, Gi24, VISTA
• Alternative_names
  VISTA protein, human VISTA protein, human recombinant VISTA protein, recombinant VISTA protein, human cell expressed VISTA protein, Human Cellexp Human Recombinant VISTA, Human recombinant VISTA, Human recombinant VISTA, Human VISTA, Human VISTA, Recombinant VISTA, Recombinant VISTA, VISTA, B7-H5, VISTA human, B7-H5 human, rhVISTA, rhB7-H5, rh Gi24, rh Gi24, rh-VISTA, rh-B7-H5, hVISTA, hB7-H5, h Gi24, March-RP-16
• Description
  Platelet receptor Gi25
• Recombinant
  Yes
• Source
  HEK 293 cells
• Purity by SDS PAGE
  >95%
• Assay
  SDS-PAGE
• Purity
  >95%
• Endotoxin Level
  < 1 EU/ug
• Molecular Weight
  This protein is fused with a Fc tag at C-terminus and has a calculated MW of 20 kDa.
• Storage Temp
  -20°C
• Shipping
  Gel pack
• Shelf Life
  12 months
• Appearance
  Lyophilized
• Physical form description
  Lyophilized
• Reconstitution Instructions
  Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 ug/ml
• Background Information
  Platelet receptor Gi24, also known as B7-H5 and stress-induced secreted protein-1 (Sisp-1), is a protein that in humans is encoded by the C10orf54 gene, which contains 1 Ig-like (immunoglobulin-like) domain. As for C10orf54 gene, C10orf54 appears to positively interact with BMP-4, potentiating BMP signaling and the transition from an undifferentiated to a differentiated state on ESCs. Human C10orf54 undergoes proteolytic cleavage by MT1-MMP, generating a soluble 30 kDa extracellular fragment plus a 25-30 kDa membrane-bound fragment.
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  CellExp™   B7-H5   VISTA  
• Gene symbol
  VSIR, HHLA2, NME5, RNY4P2, LRRC23, PCDHGB7, NCR3LG1, CD274, CD86, SEPTIN5
• Short name
  CellExp™ B7-H5 / VISTA, recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Humans
• Alternative name
  H. sapiens CellExp™ B7-H5 / VISTA, H. sapiens Rec.
• Alternative technique
  rec

Gene info

• Identity
  HGNC:30085
• Gene
  VSIR
• Long gene name
  V-set immunoregulatory receptor
• Synonyms gene
  • C10orf54
• Synonyms gene name
  • chromosome 10 open reading frame 54
• Synonyms
  • SISP1
  • GI24
  • B7-H5
  • B7H5
  • VISTA
  • PD-1H
  • Dies1
• Synonyms name
  • stress induced secreted protein 1
  • V-domain Ig suppressor of T cell activation
  • PDCD1 homolog
• GenBank acession
  • AF193048
• Locus
  10q22.1
• Discovery year
  2005-10-06
• Entrez gene record
  64115
• Pubmed identfication
  • 12975309
  • 24691993
  • 25279955
• RefSeq identity
  • NM_022153
• Classification
  • B7 family
  • V-set domain containing
• VEGA ID
  OTTHUMG00000018426

Gene info

• Identity
  HGNC:4905
• Gene
  HHLA2
• Long gene name
  HERV-H LTR-associating 2
• Synonyms
  • B7H7
  • B7-H5
  • B7y
  • B7-H7
• GenBank acession
  • AF126162
• Locus
  3q13.13
• Discovery year
  1999-09-07
• Entrez gene record
  11148
• Pubmed identfication
  • 10444326
  • 23784006
  • 22488247
• RefSeq identity
  • NM_007072
• Classification
  • C1-set domain containing
  • V-set domain containing
  • B7 family
• VEGA ID
  OTTHUMG00000159224

Gene info

• Identity
  HGNC:7853
• Gene
  NME5
• Long gene name
  NME/NM23 family member 5
• Synonyms gene name
  • non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase)
• Synonyms
  • nm23-H5
  • RSPH23
• Synonyms name
  • radial spoke 23 homolog (Chlamydomonas)
• GenBank acession
  • Y14992
• Locus
  5q31.2
• Discovery year
  1998-02-26
• Entrez gene record
  8382
• Pubmed identfication
  • 9742940
  • 19852809
• RefSeq identity
  • NM_003551
• Classification
  • NME/NM23 family
• VEGA ID
  OTTHUMG00000129207

Gene info

• Identity
  HGNC:10246
• Gene
  RNY4P2
• Long gene name
  RNY4 pseudogene 2
• Synonyms gene name
  • RNA, Y4 small cytoplasmic (associated with Ro protein) pseudogene 2
  • RNA, Ro-associated Y4 pseudogene 2
• Synonyms
  • hY4.B7
• GenBank acession
  • M77130
• Locus
  17q21.31
• Discovery year
  1993-08-25
• Entrez gene record
  6088
• RefSeq identity
  • NG_005037

Gene info

• Identity
  HGNC:19138
• Gene
  LRRC23
• Long gene name
  leucine rich repeat containing 23
• Synonyms
  • B7
  • LRPB7
• GenBank acession
  • BC014450
• Locus
  12p13.31
• Discovery year
  2006-01-24
• Entrez gene record
  10233
• Pubmed identfication
  • 11830501
  • 11826754
• RefSeq identity
  • NM_006992
• VEGA ID
  OTTHUMG00000156668

Gene info

• Identity
  HGNC:8714
• Gene
  PCDHGB7
• Long gene name
  protocadherin gamma subfamily B, 7
• Synonyms
  • ME6
  • PCDH-GAMMA-B7
• Synonyms name
  • cadherin ME6
• GenBank acession
  • AF152523
• Locus
  5q31.3
• Discovery year
  2000-06-28
• Entrez gene record
  56099
• Pubmed identfication
  • 10380929
• RefSeq identity
  • NM_018927
• Classification
  • Clustered protocadherins
• VEGA ID
  OTTHUMG00000164054

Gene info

• Identity
  HGNC:42400
• Gene
  NCR3LG1
• Long gene name
  natural killer cell cytotoxicity receptor 3 ligand 1
• Synonyms
  • DKFZp686O24166
  • B7-H6
• Synonyms name
  • B7 homolog 6
• Locus
  11p15.1
• Discovery year
  2012-04-12
• Entrez gene record
  374383
• Pubmed identfication
  • 19528259
• RefSeq identity
  • NM_001202439
• Classification
  • Receptor ligands
  • C1-set domain containing
  • B7 family
• VEGA ID
  OTTHUMG00000165913

Gene info

• Identity
  HGNC:17635
• Gene
  CD274
• Long gene name
  CD274 molecule
• Synonyms gene
  • PDCD1LG1
• Synonyms gene name
  • programmed cell death 1 ligand 1
  • CD274 antigen
• Synonyms
  • B7-H
  • B7H1
  • PD-L1
  • PDL1
  • B7-H1
• Synonyms name
  • B7 homolog 1
• GenBank acession
  • AF177937
• Locus
  9p24.1
• Discovery year
  2003-11-13
• Entrez gene record
  29126
• Pubmed identfication
  • 11015443
  • 10581077
• RefSeq identity
  • NM_014143
• Classification
  • Receptor ligands
  • C2-set domain containing
  • V-set domain containing
  • B7 family
  • CD molecules
• VEGA ID
  OTTHUMG00000019503

Gene info

• Identity
  HGNC:1705
• Gene
  CD86
• Long gene name
  CD86 molecule
• Synonyms gene
  • CD28LG2
• Synonyms gene name
  • CD86 antigen (CD28 antigen ligand 2, B7-2 antigen)
• Synonyms
  • B7.2
  • B7-2
• Synonyms name
  • B-lymphocyte antigen B7-2
• Locus
  3q13.33
• Discovery year
  1994-12-07
• Entrez gene record
  942
• Pubmed identfication
  • 7513726
• RefSeq identity
  • NM_006889
• Classification
  • B7 family
  • CD molecules
  • V-set domain containing
• VEGA ID
  OTTHUMG00000159482

Gene info

• Identity
  HGNC:9164
• Gene
  SEPTIN5
• Long gene name
  septin 5
• Synonyms gene
  • PNUTL1
  • SEPT5
• Synonyms gene name
  • peanut-like 1 (Drosophila)
• Synonyms
  • HCDCREL-1
  • H5
• GenBank acession
  • Y11593
• Locus
  22q11.21
• Discovery year
  1998-07-15
• Entrez gene record
  5413
• Pubmed identfication
  • 9385360
  • 9611266
• RefSeq identity
  • NM_002688
• Classification
  • Septins
• VEGA ID
  OTTHUMG00000150399

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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