anti- BAK antibody

• Catalog number
  FNab00796
• Price
  Please ask
• Size
  2X100μg

• Form
  liquid
• Purification
  Immunogen affinity purified
• Purity
  ≥95% as determined by SDS-PAGE
• Storage
  PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
• Background
  The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.
• Immunogen
  BCL2-antagonist/killer 1
• Synonyms
  Apoptosis regulator BAK, BAK, BAK LIKE, BAK1, CDN1
• Calculated MW
  Refer to figures
• Uniprot ID
  Q16611
• Specificity
  Human, Rat
• Tested Application
  ELISA, WB, IHC
• Recommended dilution
  WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
• Image1
  Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using FNab00796( BAK Antibody) at dilution of 1:200
• Image4
  A431 cells were subjected to SDS PAGE followed by western blot with FNab00796(BAK antibody) at dilution of 1:1000
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• Properties
  If you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  BAK  
• Gene symbol
  BAK1
• Short name
  anti- BAK antibody
• Technique
  Antibody, anti, antibody to, antibodies against human proteins, antibodies for
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  antibody to- BAK (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:949
• Gene
  BAK1
• Long gene name
  BCL2 antagonist/killer 1
• Synonyms gene
  • CDN1
• Synonyms gene name
  • BCL2-antagonist/killer 1
• Synonyms
  • BCL2L7
  • BAK
• GenBank acession
  • U23765
• Locus
  6p21.31
• Discovery year
  1997-10-09
• Entrez gene record
  578
• Pubmed identfication
  • 7715730
  • 7715731
• RefSeq identity
  • NM_001188
• Classification
  • BCL2 family
• VEGA ID
  OTTHUMG00000014530

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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