Anti-Calcineurin B/PP2B-B1, ALEXA Fluor 594
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Catalog numberGENTObs-11246R-A594
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PricePlease ask
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Size100 microliters
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TypeConjugated Primary Antibody
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Conjugated withALEXA FLUOR® 594
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Host organismRabbit (Oryctolagus cuniculus)
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Target Protein PeptideCalcineurin B/PP2B-B1
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SpecificityThis antibody reacts specifically with Calcineurin B/PP2B-B1
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ModificationNo modification has been applied to this antibody
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Modification siteNone
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ClonalityPolyclonal Antibody
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ClonePolyclonal Antibodies
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Concentration1ug per 1ul
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Subcellular locationsN/A
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Antigen SourceKLH conjugated synthetic peptide derived from human Calcineurin B/PP2B-B1
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Gene IDN/A
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Swiss ProtN/A
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ApplicationsIF(IHC-P)
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Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
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Cross reactive speciesHuman (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
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Cross Reactive Species detailsNo significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
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Background informationIn eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. Four major families of protein phosphatase catalytic subunit have been identified, designated PP1, PP2A, PP2B and PP2C. An additional protein phosphatase catalytic subunit, PPX (also known as PP4), is a putative member of a novel PP family. The PP2B family comprises subfamily members PP2B-A alpha, PP2B-A Beta and PP2B-A Gamma. Two additional regulatory subunits been identified, designated PP2B-B1 and PP2B-B2.
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Purification methodPurified by Protein A.
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StorageWater buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
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Excitation emission590nm/617nm
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SynonymsCalcineurin subunit B type 1; CALNB1; CANB1_HUMAN; Cna2; CNB; CNB1; OTTHUMP00000201960; OTTHUMP00000201961; Ppp3r1; PPP3R1 protein phosphatase 3 formerly 2B, regulatory subunit B, alpha isoform; alpha isoform calcineurin B, type I; calcineurin B, type I 19kDa; protein phosphatase3 formerly2B, regulatory subunit B, alpha isoform antibody Protein phosphatase 2B regulatory subunit 1; Protein phosphatase 2B regulatory subunit B alpha; protein phosphatase 3 formerly 2B, regulatory subunit B, 19kDa, alpha isoform calcineurin B, type I; Protein phosphatase 3 regulatory subunit B alpha; Protein phosphatase 3 regulatory subunit B alpha isoform 1.
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Also known asCalcineurin B/PP2B-B1 Antibody
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Other nameAnti-Calcineurin B/PP2B-B1
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AdvisoryAvoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
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PropertiesFor facs or microscopy Alexa 1 conjugate.
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ConjugationAlexa Fluor, ALEXA FLUOR® 594
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ConjugatedAlexa conjugate 1
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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Gene target
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Gene symbolBBS9, SNAR-B1, PCDHGB1, STON1, MS4A1, SH3GL2, VCX, NABP2
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Short nameAnti-Calcineurin B/PP2B-B1
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Techniqueanti-, anti, antibody to, antibodies
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IsotypeImmunoglobulin G (IgG)
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LabelALEXA FLUOR 594
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Alternative nameCalcineurin B/PP2B-B1 Antibody, ALEXA FLUOR® 594 Conjugated
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameBardet-Biedl syndrome 9
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Synonyms
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Synonyms name
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Locus
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Discovery year2007-01-18
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Entrez gene record
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Pubmed identfication
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Classification
- BBSome
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namesmall NF90 (ILF3) associated RNA B1
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Synonyms gene name
- small ILF3/NF90-associated RNA B1
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GenBank acession
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Locus
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Discovery year2008-07-03
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Small NF90 (ILF3) associated RNAs
Gene info
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Identity
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Gene
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Long gene nameprotocadherin gamma subfamily B, 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2000-06-28
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Clustered protocadherins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namestonin 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2006-02-10
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemembrane spanning 4-domains A1
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Synonyms gene
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Synonyms gene name
- membrane-spanning 4-domains, subfamily A, member 1
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Synonyms
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GenBank acession
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Locus
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Discovery year1989-05-23
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Entrez gene record
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Pubmed identfication
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Classification
- Membrane spanning 4-domains
- CD molecules
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameSH3 domain containing GRB2 like 2, endophilin A1
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Synonyms gene name
- SH3 domain containing GRB2 like 2
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1996-10-26
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- N-BAR domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namevariable charge X-linked
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Synonyms gene name
- variable charge, X chromosome
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-03-03
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Variable charge X/Y family
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namenucleic acid binding protein 2
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Synonyms gene
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Synonyms gene name
- oligonucleotide/oligosaccharide-binding fold containing 2B
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2006-01-17
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Entrez gene record
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RefSeq identity
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data