E6005 (RVT-501)

• Catalog number
  B2263-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  Methyl 4-((3-(6,7-dimethoxy-2-(methylamino)quinazolin-4-yl)phenyl)carbamoyl)benzoate; Lotamilast
• Description
  E6005 (RVT 501), a selective phosphodiesterase 4 (PDE4) inhibitor, developed for the treatment of atopic dermatitis.
• CAS Number
  947620-48-6
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₆H₂₄N₄O₅
• Molecular Weight
  472.5
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO
• Handling
  Protect from air and light
• Tag Line
  A selective phosphodiesterase 4 (PDE4) inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  24864553
• PubChem CID Link
• SMILES
  CNC1=NC2=CC(=C(C=C2C(=N1)C3=CC(=CC=C3)NC(=O)C4=CC=C(C=C4)C(=O)OC)OC)OC
• InChi
  InChI=1S/C26H24N4O5/c1-27-26-29-20-14-22(34-3)21(33-2)13-19(20)23(30-26)17-6-5-7-18(12-17)28-24(31)15-8-10-16(11-9-15)25(32)35-4/h5-14H,1-4H3,(H,28,31)(H,27,29,30)
• InChi Key
  BBTFKAOFCSOZMB-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  YES

• Gene target
  E6005   RVT-501  
• Gene symbol
  MIR501
• Short name
  E6005 (RVT-501)
• Alternative name
  E6005 (RVT-501)

Gene info

• Identity
  HGNC:32135
• Gene
  MIR501
• Long gene name
  microRNA 501
• Synonyms gene
  • MIRN501
• Synonyms
  • hsa-mir-501
• Locus
  Xp11.23
• Discovery year
  2005-07-15
• Entrez gene record
  574503
• RefSeq identity
  • NR_030225
• Classification
  • MicroRNA MIR500 family

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