CD43 (T-Cell Marker) Mouse Monoclonal Antibody

• Catalog number
  MBS438321
• Price
  Please ask
• Size
  0.02 mg (With BSA & Azide at 0.2mg/mL)

• Products_type
  Antibody
• Products_short_name
  [CD43]
• Products_name_syn
  [Galactoglycoprotein, GALGP, GPL115, Leukocyte sialoglycoprotein, Leukosialin, LSN, Sialophorin, SPN]
• Other_names
  [leukosialin; Leukosialin; leukosialin; sialophorin; Galactoglycoprotein; GALGP; Leukocyte sialoglycoprotein; Sialophorin; CD_antigen: CD43]
• Products_gene_name
  [SPN]
• Other_gene_names
  [SPN; SPN; LSN; CD43; GALGP; GPL115; CD43; GALGP]
• Clonality
  Monoclonal
• Clone
  [DF-T1]
• Reactivity
  Human
• Specificity
  It recognizes a cell surface glycoprotein of 95/115/135kDa (depending upon the extent of glycosylation), identified as CD43 [Workshop IV]. Epitope of MAb Bra7G is clearly different from that of MAb DF-T1, called b as opposed to a for DF-T1. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors of lymphoma.
• Form
  200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Storage_stability
  Antibody with azide - store at 2 to 8 degree C. Antibody without azide - store at -20 to -80 degree C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
• Tested_application
  Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin
• Properties
  If you buy Antibodies supplied by MyBioSource they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Description
  For cells, cell lines and tissues in culture till half confluency.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus
• French translation
  anticorps

• Gene target
  CD43   Monoclonal  
• Gene symbol
  SPN
• Short name
  CD43 (T- ) Mouse Monoclonal Antibody
• Technique
  Mouse monoclonal, Antibody, Mouse, antibodies against human proteins, antibodies for, Component cell markers and DNA bp. markers are genetic markers er genes or DNA sequences with a known location on a chromosome that can be used to identify individuals or species. Protein markers in kDA. Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
• Host
  Mouse, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
• Isotype
  IgG1, kappa
• Species
  Mouse, Mouses
• Alternative name
  CD43 (T-cellular detection labelled) Mouse monoclonal (antibody to-)
• Alternative technique
  antibodies, murine
• Tissue
  cell

Gene info

• Identity
  HGNC:11249
• Gene
  SPN
• Long gene name
  sialophorin
• Synonyms gene name
  • sialophorin (gpL115, leukosialin, CD43)
• Synonyms
  • LSN
  • CD43
  • GPL115
• Synonyms name
  • leukosialin
• GenBank acession
  • J04536
• Locus
  16p11.2
• Discovery year
  1988-08-31
• Pubmed identfication
  • 2784859
  • 2521952
• Classification
  • CD molecules
• VEGA ID
  OTTHUMG00000097765

MeSH Data

• Name
  CD4 Lymphocyte Count
• Concept
  Scope note: The number of CD4-POSITIVE T-LYMPHOCYTES per unit volume of BLOOD. Determination requires the use of a fluorescence-activated flow cytometer.
• Tree numbers
  • E01.370.225.500.195.107.595.500.150
  • E01.370.225.625.107.595.500.150
  • E05.200.500.195.107.595.500.150
  • E05.200.625.107.595.500.150
  • E05.242.195.107.595.500.150
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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