CGP-57380

• Catalog number
  9661-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  N3-(4-Fluorophenyl)-1H-pyrazolo-[3,4-d]pyrimidine-3,4-diamine
• Description
  CGP-57380 is a cell-permeable Inhibitor of MAP-kinase interacting kinase-1 (Mnk1, MKNK1) (IC₅₀ = 2.2 μM). Displays selectivity over p38, JNK1, ERK1, ERK2, PKC and c-src family kinases.
• CAS Number
  522629-08-9
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₁H₉FN₆
• Molecular Weight
  244.23
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (>20 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A potent Inhibitor of MAP-kinase interacting kinase-1 (Mnk1)
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  11644425
• PubChem CID Link
• SMILES
  C1=CC(=CC=C1NC2=C3C(=NC=NC3=NN2)N)F
• InChi
  InChI=1S/C11H9FN6/c12-6-1-3-7(4-2-6)16-11-8-9(13)14-5-15-10(8)17-18-11/h1-5H,(H4,13,14,15,16,17,18)
• InChi Key
  UQPMANVRZYYQMD-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  CGP-57380  
• Short name
  CGP-57380
• Alternative name
  CGP-57380

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