Mek1/2 Antibody

• Catalog number
  3518-100
• Price
  Please ask
• Size
  100 µl

• Antibody Target
  Mek 1/2
• Target Alternative Name
  MAPK , Erk, Dual specificity mitogen-activated protein kinase kinase 1/2; MAP kinase kinase 1/2; MAPKK 1/2; ERK activator kinase 1/2; MAPK/ERK kinase 1/2; MEK 1/2
• Antibody Type
  Polyclonal
• Species Reactivities
  Human, mouse, rat
• Immunogen Sequence
  Synthetic peptide from human Mek1/2
• Accession
  NP_002746.1
• Gene Id
  5579478
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  0.5 mg/ml
• Formulation
  100 µl purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 50% glycerol, 1% BSA, and 0.02% sodium azide.
• Purification
  Affinity purified
• Application
  Western blot
• Application And Usages
  Western blotting (1:500-1000). However, the optimal concentrations should be determined individually. The antibody recognizes 45 kDa Mek1/2 of human, mouse, and rat origins.
• Description
  MAP kinase kinase 1 (Mek1), also known as mitogen activated protein kinase kinase, MAP kinase kinase, ERK kinase 1 or microtubule-associated protein 2 kinase, is a 43 kDa dual-specificity protein kinase that phosphorylates threonine and tyrosine residues on MAP kinases such as Erk 1 and 2. Mek1 and Mek2 are involved in a diverse array of cellular processes such as stress-activated response, apoptosis, cytokine-induced cell proliferation, and DNA recombination during meiosis. Mek1 and Mek2 are activated by phosphorylation on serine 218 and 222 by serine-threonine kinase, Raf-1, which is part of the p21ras signal transduction pathway.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Mek1/2  
• Gene symbol
  PPP4R3B
• Short name
  Mek1/2 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Mek1/2 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:29267
• Gene
  PPP4R3B
• Long gene name
  protein phosphatase 4 regulatory subunit 3B
• Synonyms gene
  • SMEK2
• Synonyms gene name
  • SMEK homolog 2, suppressor of mek1 (Dictyostelium)
  • protein phosphatase 4, regulatory subunit 3B
• Synonyms
  • PSY2
  • FLFL2
  • KIAA1387
  • FLJ31474
• GenBank acession
  • AB037808
• Locus
  2p16.1
• Discovery year
  2006-10-12
• Entrez gene record
  57223
• Pubmed identfication
  • 16085932
  • 18614045
• RefSeq identity
  • NM_020463
• Classification
  • Armadillo like helical domain containing
• VEGA ID
  OTTHUMG00000129336

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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