Selonsertib

• Catalog number
  B1312-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  5-(4-cyclopropyl-1H-imidazol-1-yl)-2-fluoro-N-(6-(4-isopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-yl)-4-methylbenzamide; GS-4997
• Description
  Selonsertib is a potent inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with potential anti-inflammatory, antineoplastic and anti-fibrotic activities. GS-4997 targets and binds to the catalytic kinase domain of ASK1 in an ATP-competitive manner, thereby preventing its phosphorylation and activation.
• CAS Number
  1448428-04-3
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₄H₂₄FN₇O
• Molecular Weight
  445.5
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO
• Handling
  Protect from air and light
• Tag Line
  A potent apoptosis signal-regulating kinase 1 (ASK1) inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  71245288
• PubChem CID Link
• SMILES
  CC1=C(C=C(C(=C1)F)C(=O)NC2=CC=CC(=N2)C3=NN=CN3C(C)C)N4C=C(N=C4)C5CC5
• InChi
  InChI=1S/C24H24FN7O/c1-14(2)32-13-27-30-23(32)19-5-4-6-22(28-19)29-24(33)17-10-21(15(3)9-18(17)25)31-11-20(26-12-31)16-7-8-16/h4-6,9-14,16H,7-8H2,1-3H3,(H,28,29,33)
• InChi Key
  YIDDLAAKOYYGJG-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Selonsertib  
• Short name
  Selonsertib
• Alternative name
  Selonsertib

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