Anti-NOTCH 3 Antibody
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Catalog numberA1653-100
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PricePlease ask
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Size100 µl
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Antibody TargetNOTCH 3
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Target Alternative NameNeurogenic locus notch homolog protein 3; Notch 3
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Antibody TypePolyclonal
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Species ReactivitiesHuman, Mouse, Rat
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Immunogen SequenceKLH-conjugated synthetic peptide encompassing a sequence within the center region of human NOTCH3
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AccessionQ9UM47
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Gene Id4854
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AppearanceColorless liquid
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FormLiquid
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Concentration1 mg/ml
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FormulationIn 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol and 0.01% sodium azide
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PurificationAffinity purified
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ApplicationWB
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Positive ControlWB: Western blot analysis of NOTCH3 expression in A549 (A); NS-1 (B); PC12 (C) whole cell lysates.
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Application And UsagesWB; 1:500 – 1:1000
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DescriptionFunctions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs.
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life12 months
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UsageFor Research Use Only! Not to be used in humans.
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HandlingThe antibody solution should be gently mixed before use.
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Western Blot VerifiedVerified
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Immunocytochemistry VerifiedNot Verified
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Immunofluorescence VerifiedNot Verified
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Immunoprecipitation VerifiedNot Verified
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FACS VerifiedNot Verified
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ELISA VerifiedNot Verified
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ChIP VerifiedNot Verified
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Dot Blot VerifiedNot Verified
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Flow Cytometry VerifiedNot Verified
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Additional descriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolNOTCH3, DLL3, TLX1
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Short nameAnti-NOTCH 3 Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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IsotypeRabbit IgG
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Alternative nameAntibody toNOTCH 3 (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene namenotch receptor 3
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Synonyms gene
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Synonyms gene name
- Notch (Drosophila) homolog 3
- Notch homolog 3 (Drosophila)
- notch 3
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Synonyms
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GenBank acession
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Locus
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Discovery year1994-07-04
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Notch receptors
- MicroRNA protein coding host genes
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namedelta like canonical Notch ligand 3
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Synonyms gene name
- delta (Drosophila)-like 3
- delta-like 3 (Drosophila)
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-03-15
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Entrez gene record
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Pubmed identfication
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameT cell leukemia homeobox 1
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Synonyms gene
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Synonyms gene name
- homeo box 11 (T-cell lymphoma 3-associated breakpoint)
- T-cell leukemia, homeobox 1
- T-cell leukemia homeobox 1
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Synonyms name
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GenBank acession
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Locus
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Discovery year1991-03-18
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- NKL subclass homeoboxes and pseudogenes
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data