BAFF, Soluble (60-mer), Recombinant, Human(highly active) (BLyS, TALL-1, CD257, B Cell Activating Factor, TNFSF13B, Tumor Necrosis Factor Ligand Superfamily Member 13B)[BAFF, Soluble]

• Catalog number
  MBS636788
• Price
  Please ask
• Size
  NA

• Products_type
  Recombinant Protein
• Description
  For cells, cell lines and tissues in culture till half confluency. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  BAFF   Soluble   60-mer   highly   active   BLyS   TALL-1   CD257   Activating   Factor   TNFSF13B   Tumor   Necrosis   Factor   Ligand   Superfamily   Member   13B   [BAFF   Soluble]  
• Gene symbol
  TNFSF13B, IGHVII-60-1, IGLV4-60, IGHV3-60, RCC2, OGFR, RNU6-60P, SPINK4, USP32, PPIL2
• Short name
  BAFF, Soluble (60-mer), Recombinant, (highly active) (BLyS, TALL-1, CD257, B Activating Factor, TNFSF13B, Tumor Necrosis Factor Ligand Superfamily Member 13B)[BAFF, Soluble]
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Host
  E. Coli
• Species
  Human, Humans
• Alternative name
  BAFF, Soluble (60-mer), Rec., H. sapiens(very functionnal) (BLyS, TALL-1, CD257, B cellular Activating Factor, tumor necrosis factor (ligand) superfamily, member 13b, Tumor Necrosis Factor Ligand supergroup Member 13B)[BAFF, Soluble]
• Alternative technique
  rec
• Alternative to gene target
  tumor necrosis factor (ligand) superfamily, member 13b, BAFF and BLYS and CD257 and DTL and TALL-1 and TALL1 and THANK and TNFSF20 and ZTNF4, TNFSF13B and IDBG-49841 and ENSG00000102524 and 10673, protein binding, Extracellular, Tnfsf13b and IDBG-131999 and ENSMUSG00000031497 and 24099, BT.24855 and IDBG-633619 and ENSBTAG00000011563 and 504507
• Tissue
  cell, tumor

Gene info

• Identity
  HGNC:11929
• Gene
  TNFSF13B
• Long gene name
  TNF superfamily member 13b
• Synonyms gene
  • TNFSF20
• Synonyms gene name
  • tumor necrosis factor (ligand) superfamily, member 13b
• Synonyms
  • BAFF
  • THANK
  • BLYS
  • TALL-1
  • TALL1
  • CD257
• Synonyms name
  • B-cell-activating factor
  • TNF and ApoL-related leukocyte expressed ligand 1
  • TNF homolog that activates apoptosis
  • B-lymphocyte stimulator
• GenBank acession
  • AF136293
• Locus
  13q33.3
• Discovery year
  1999-07-19
• Entrez gene record
  10673
• Pubmed identfication
  • 10331498
  • 10359578
• RefSeq identity
  • NM_006573
• Classification
  • CD molecules
  • Tumor necrosis factor superfamily
• VEGA ID
  OTTHUMG00000017329

Gene info

• Identity
  HGNC:5686
• Gene
  IGHVII-60-1
• Long gene name
  immunoglobulin heavy variable (II)-60-1 (pseudogene)
• Synonyms gene name
  • immunoglobulin heavy variable (II)-60-1
  • immunoglobulin heavy variable (II)-60-1 pseudogene
• Synonyms
  • IGHV(II)-60-1
• GenBank acession
  • AB019437
• Locus
  14q32.33
• Discovery year
  2000-04-17
• Entrez gene record
  28361
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000151951

Gene info

• Identity
  HGNC:5920
• Gene
  IGLV4-60
• Long gene name
  immunoglobulin lambda variable 4-60
• GenBank acession
  • Z73667
• Locus
  22q11.22
• Discovery year
  2000-05-08
• Entrez gene record
  28785
• RefSeq identity
  • NG_000002
• Classification
  • Immunoglobulin lambda locus at 22q11.2
• VEGA ID
  OTTHUMG00000150851

Gene info

• Identity
  HGNC:5614
• Gene
  IGHV3-60
• Long gene name
  immunoglobulin heavy variable 3-60 (pseudogene)
• Synonyms gene name
  • immunoglobulin heavy variable 3-60
  • immunoglobulin heavy variable 3-60 pseudogene
• GenBank acession
  • M29813
• Locus
  14q32.33
• Discovery year
  2000-04-04
• Entrez gene record
  28417
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000151956

Gene info

• Identity
  HGNC:30297
• Gene
  RCC2
• Long gene name
  regulator of chromosome condensation 2
• Synonyms
  • TD-60
• Locus
  1p36.13
• Discovery year
  2005-06-07
• Entrez gene record
  55920
• Pubmed identfication
  • 10819331
  • 12919680
• RefSeq identity
  • NM_018715
• VEGA ID
  OTTHUMG00000002513

Gene info

• Identity
  HGNC:15768
• Gene
  OGFR
• Long gene name
  opioid growth factor receptor
• Synonyms
  • 7-60
• GenBank acession
  • AF109134
• Locus
  20q13.33
• Discovery year
  2001-05-31
• Entrez gene record
  11054
• Pubmed identfication
  • 10677613
  • 26687326
• VEGA ID
  OTTHUMG00000032937

Gene info

• Identity
  HGNC:42550
• Gene
  RNU6-60P
• Long gene name
  RNA, U6 small nuclear 60, pseudogene
• Synonyms gene
  • RNU6-60
• Synonyms gene name
  • RNA, U6 small nuclear 60
• Locus
  13q14.2
• Discovery year
  2011-08-08
• Entrez gene record
  106480750

Gene info

• Identity
  HGNC:16646
• Gene
  SPINK4
• Long gene name
  serine peptidase inhibitor Kazal type 4
• Synonyms gene name
  • serine protease inhibitor, Kazal type 4
• Synonyms
  • PEC-60
  • MGC133107
• GenBank acession
  • AF048700
• Locus
  9p13.3
• Discovery year
  2001-09-21
• Entrez gene record
  27290
• Pubmed identfication
  • 1400298
  • 17333166
• RefSeq identity
  • NM_014471
• Classification
  • Serine peptidase inhibitors, Kazal type
• VEGA ID
  OTTHUMG00000019762

Gene info

• Identity
  HGNC:19143
• Gene
  USP32
• Long gene name
  ubiquitin specific peptidase 32
• Synonyms gene name
  • ubiquitin specific protease 32
• Synonyms
  • NY-REN-60
  • USP10
• GenBank acession
  • AF533230
• Locus
  17q23.3
• Discovery year
  2003-05-29
• Entrez gene record
  84669
• Pubmed identfication
  • 12838346
• RefSeq identity
  • NM_032582
• Classification
  • EF-hand domain containing
  • Ubiquitin specific peptidases
• VEGA ID
  OTTHUMG00000180001

Gene info

• Identity
  HGNC:9261
• Gene
  PPIL2
• Long gene name
  peptidylprolyl isomerase like 2
• Synonyms gene name
  • peptidylprolyl isomerase (cyclophilin)-like 2
• Synonyms
  • UBOX7
  • CYC4
  • Cyp-60
• Synonyms name
  • U-box domain containing 7
  • peptidyl-prolyl cis-trans isomerase-like 2
• Locus
  22q11.21
• Discovery year
  1999-10-29
• Entrez gene record
  23759
• Pubmed identfication
  • 10591208
• Classification
  • Spliceosomal Bact complex
  • U-box domain containing
  • Cyclophilin peptidylprolyl isomerases
• VEGA ID
  OTTHUMG00000191763

MeSH Data

• Name
  Tumor Stem Cell Assay
• Concept
  Scope note: A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
• Tree numbers
  • E01.370.225.500.383.910
  • E01.370.225.500.388.930
  • E05.200.500.383.910
  • E05.200.500.388.930
  • E05.242.383.910
  • E05.242.417.500
  • E05.337.550.200.800
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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