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Long name
Nicotinic Receptor, beta 4, aa490-498
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Antigen
Nicotinic Receptor, beta 4, aa490-498
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Synonim names
Anti -Nicotinic Receptor, beta 4, aa490-498
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Other names
neuronal acetylcholine receptor subunit alpha-3 isoform 1; Neuronal acetylcholine receptor subunit alpha-3; neuronal acetylcholine receptor subunit alpha-3; cholinergic receptor, nicotinic, alpha polypeptide 3; neuronal nicotinic acetylcholine receptor, alpha3 subunit; cholinergic receptor, nicotinic, alpha 3 (neuronal); N/A
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Gene name
Nicotinic Receptor, beta 4, aa490-498
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Gene synonims
CHRNA3; CHRNA3; LNCR2; PAOD2; NACHRA3; NACHRA3
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Category
Antibodies
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Clonality
Polyclonal Antibodies
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Clone
Not applicable to Polyclonal Antibodies
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Reacts with
Human (Homo sapiens)
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Specificity
Recognizes human Nicotinic beta4 receptor (490-498) and the reactivity of Nicotinic beta4 receptor is ~80%. Does not react to Nicotinic alpha3 receptor, Nicotinic alpha4 receptor, Nicotinic alpha5 receptor, Nicotinic alpha7 receptor, Nicotinic beta2 receptor and Nicotinic beta3 receptor. ;This is an antibody designed to detect Nicotinic Receptor, beta 4, aa490-498
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Purification method
Highly PurifiedPurified by precipitation, dialysis and chromatography.
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Form Appearance
Supplied as a lyophilized powder. Reconstitution with 5.0 ml of TBS/Tween-20.
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Concentration
Enquire us for detailed information on the concentration of this antibody
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Storage shipping and handling
Lyophilized powder may be stored at 4 degree C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. The antibody is shipped at +4 degrees Celsius. Upon receving, freeze at -20. For longer periods of time we recommend keeping the vial frozen at -40 or -80. Avoid cycles of freezing and thawing as they may denaturate the polypeptide chains of the antibody. Due to transportation or handling reasons, small amounts of the antibody might get caught on the lid or walls of the vial. Further dilutions can be made in assay buffer.
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Applications
Western Blot (WB)
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Properties
If you buy Antibodies supplied by MBS Polyclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
