HDAC4 + 5 + 9 Antibody, ALEXA FLUOR 555
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Catalog number
bs-12156R-A555
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Price
Please ask
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Size
100ul
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Long name
HDAC4 + 5 + 9 Polyclonal Antibody, ALEXA FLUOR 555 Conjugated
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Also known as
Anti-HDAC4 + 5 + 9 PAb ALEXA FLUOR 555
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Category
Conjugated Primary Antibodies
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Conjugated with
ALEXA FLUOR® 555
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Host Organism
Rabbit (Oryctolagus cuniculus)
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Target Antigen
HDAC4 + 5 + 9
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Specificity
This is a highly specific antibody against HDAC4 + 5 + 9.
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Modification
Unmodified
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Modification Site
None
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Clonality
Polyclonal
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Clone
Polyclonal antibody
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Concentration
1ug per 1ul
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Source
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HDAC4 + 5 + 9
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Tested applications
IF(IHC-P)
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Recommended dilutions
IF(IHC-P)(1:50-200)
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Crossreactivity
Human, Mouse, Rat
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Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the antigen
In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. Conversely, the deacetylation of histones is associated with transcriptional silencing. Several mammalian proteins have been identified as nuclear histone acetylases, including GCN5, PCAF (p300/CBP-associated factor), p300/CBP, HAT1, and the TFIID subunit TAF II p250. Mammalian HDAC1 (also designated HD1), HDAC2 (also designated RPD3) and HDAC3-7, have been identified as histone deacetylases. Mammalian HDAC7 interacts with the adaptor mSin3A. The interaction of HDAC7 with mSin3A suggests the association of multiple repression complexes of transcription factors.
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Purification
Purified by Protein A.
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Storage conditions
Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
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Excitation emission
553nm/568nm
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Synonyms
AHO3 ;Antigen NY-CO-9 ;BDMR ;HA6116 ;HD4 ;HD5 ;HD7 ;HD7b ;HD9 ;HDAC ;HDAC-4 ;HDACA ;HDAC4 ;HDAC5 ;HDAC7 ;HDAC7B ;HDAC9 ;HDAC9B ;HDAC9FL ;HDACA ;HDRP ;Histone deacetylase 4 ;Histone deacetylase 5 ;Histone deacetylase 7B ;Histone deacetylase 9 ;Histone deacetylase-related protein ;MEF2-interacting transcription repressor MITR ;MITR ;NY-CO-9; HDAC4_HUMAN; HDAC5_HUMAN; HDAC9_HUMAN.
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Properties
For facs or microscopy Alexa 1 conjugate. Very high photo stable ALEXA conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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Conjugation
Alexa Fluor, ALEXA FLUOR 555
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French translation
anticorps
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Gene target
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Gene symbol
HDAC4-AS1, HDAC4
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Short name
Anti-HDAC4 + 5 + 9
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Technique
Antibody, antibodies against human proteins, antibodies for
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Isotype
Immunoglobulin G (IgG)
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Label
ALEXA FLUOR 555
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Alternative name
HDAC4 + 5 + 9 Polyclonal Antibody, ALEXA FLUOR 555
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Alternative technique
antibodies
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Alternative to gene target
histone deacetylase 4, AHO3 and BDMR and HA6116 and HD4 and HDAC-4 and HDAC-A and HDACA, HDAC4 and IDBG-84594 and ENSG00000068024 and 9759, NAD-dependent histone deacetylase activity (H3-K18 specific), nuclei, Hdac4 and IDBG-181579 and ENSMUSG00000026313 and 208727, HDAC4 and IDBG-642244 and ENSBTAG00000017764 and 517559
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Gene info
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Identity
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Gene
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Long gene name
HDAC4 antisense RNA 1
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Locus
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Discovery year
2018-09-27
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Entrez gene record
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RefSeq identity
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Classification
Gene info
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Identity
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Gene
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Long gene name
histone deacetylase 4
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Synonyms gene
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Synonyms gene name
- brachydactyly-mental retardation syndrome
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Synonyms
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GenBank acession
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Locus
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Discovery year
2000-11-28
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Histone deacetylases, class IIA
- MicroRNA protein coding host genes
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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