OTS-964

• Catalog number
  B1964-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  (R)-9-(4-(1-(dimethylamino)propan-2-yl)phenyl)-8-hydroxythieno[2,3-c]quinolin-4(5H)-one
• Description
  OTS-964 is a potent inhibitor of lymphokine-activated killer T cell-originated protein kinase (TOPK; IC₅₀ = 28 nM). It specifically blocks cytokinesis, leading to apoptosis, in a broad range of cancer cells. OTS-964 induces apoptosis of human lung cancer cells in mouse xenografts.
• CAS Number
  1338545-07-5
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₂H₂₂N₂O₂S
• Molecular Weight
  378.49
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO
• Handling
  Protect from air and light
• Tag Line
  A ptent inhibitor of lymphokine-activated killer T cell-originated protein kinase (TOPK)
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  67449676
• PubChem CID Link
• SMILES
  CC(CN(C)C)C1=CC=C(C=C1)C2=C(C=CC3=C2C4=C(C(=O)N3)SC=C4)O
• InChi
  InChI=1S/C22H22N2O2S/c1-13(12-24(2)3)14-4-6-15(7-5-14)19-18(25)9-8-17-20(19)16-10-11-27-21(16)22(26)23-17/h4-11,13,25H,12H2,1-3H3,(H,23,26)/t13-/m0/s1
• InChi Key
  WGYWHJPQFQGLOQ-ZDUSSCGKSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  OTS-964  
• Short name
  OTS-964
• Alternative name
  OTS-964

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