Filgotinib

• Catalog number
  2871-10
• Price
  Please ask
• Size
  10 mg

• Alternative_name
  N-(5-(4-((1,1-dioxidothiomorpholino)methyl)phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl)cyclopropanecarboxamide; GLPG0634
• Description
  Filgotinib (GLPG0634) is a potent and selective JAK1 inhibitor; displays >30-fold selectivity for JAk1 over JAK2. GLPG0634 dose-dependently inhibits Th1 and Th2 differentiation and to a lesser extent the differentiation of Th17 cells in vitro.
• CAS Number
  1206161-97-8
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₁H₂₃N₅O₃S
• Molecular Weight
  425.5
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (>25 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A potent and selective JAK1 inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  49831257
• PubChem CID Link
• SMILES
  C1CC1C(=O)NC2=NN3C(=N2)C=CC=C3C4=CC=C(C=C4)CN5CCS(=O)(=O)CC5
• InChi
  InChI=1S/C21H23N5O3S/c27-20(17-8-9-17)23-21-22-19-3-1-2-18(26(19)24-21)16-6-4-15(5-7-16)14-25-10-12-30(28,29)13-11-25/h1-7,17H,8-14H2,(H,23,24,27)
• InChi Key
  RIJLVEAXPNLDTC-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Filgotinib  
• Short name
  Filgotinib
• Alternative name
  Filgotinib

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