GBA3/CBG Antibody, ALEXA FLUOR 555

• Catalog number
  bs-13298R-A555
• Price
  Please ask
• Size
  100ul

• Long name
  GBA3/CBG Polyclonal Antibody, ALEXA FLUOR 555 Conjugated
• Also known as
  Anti-GBA3/CBG PAb ALEXA FLUOR 555
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 555
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  GBA3/CBG
• Specificity
  This is a highly specific antibody against GBA3/CBG.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GBA3/CBG
• Gene ID Number
  57733
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  CBG is a monomeric enzyme involved in the absorption and metabolism of flavonoid glucosides. CBG is found predominately in the liver, but is also located in tissues such as spleen, small intestine and kidney. Through its catalytic activity, CBG is able to hydrolyze a variety of glycosides including phytoestrogens, cyanogens, and flavonols. Although its catalytic activity extends to many dietary flavonoids, CBG has increased specificity for hydrophobic aglycones such as beta-D-glucoside and beta-D-galactoside. Hydrolysis is inhibited by sodium taurocholate and glucosyl-sphingosine, both of which regulate CBG enzymatic activity. Deficiencies in CBG have been implicated in Gaucher’s disease, a lysosomal storage disease that causes a build up of fatty material in the spleen, liver, lung and kidneys.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  553nm/568nm
• Synonyms
  CBG; CBGL1; Cytosolic beta glucosidase; Cytosolic beta glucosidase like protein 1; Cytosolic beta-glucosidase; Cytosolic beta-glucosidase-like protein 1; GBA3; GBA3_HUMAN; GLUC; Glucosidase beta acid 3; Klotho related protein.
• Properties
  For facs or microscopy Alexa 1 conjugate. Very high photo stable ALEXA conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 555
• French translation
  anticorps

• Gene target
  GBA3/CBG  
• Gene symbol
  SERPINA6, GBA3
• Short name
  Anti-GBA3/CBG
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 555
• Alternative name
  GBA3/CBG Polyclonal Antibody, ALEXA FLUOR 555
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:1540
• Gene
  SERPINA6
• Long gene name
  serpin family A member 6
• Synonyms gene
  • CBG
• Synonyms gene name
  • serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
• Synonyms name
  • corticosteroid binding globulin
  • transcortin
• GenBank acession
  • J02943
• Locus
  14q32.13
• Discovery year
  1991-08-08
• Entrez gene record
  866
• Pubmed identfication
  • 3299377
  • 7912884
  • 24172014
• RefSeq identity
  • NM_001756
• Classification
  • Serpin peptidase inhibitors
• VEGA ID
  OTTHUMG00000171346

Gene info

• Identity
  HGNC:19069
• Gene
  GBA3
• Long gene name
  glucosylceramidase beta 3 (gene/pseudogene)
• Synonyms gene name
  • glucosidase, beta, acid 3 (cytosolic)
  • glucosidase, beta, acid 3 (gene/pseudogene)
• Synonyms
  • GLUC
  • KLrP
  • CBGL1
• Synonyms name
  • klotho-related protein
  • cytosolic β-glucosidase-like protein-1
• GenBank acession
  • AB017913
• Locus
  4p15.2
• Discovery year
  2002-12-16
• Entrez gene record
  57733
• Pubmed identfication
  • 11389701
  • 17595169
• Classification
  • Glycoside hydrolase family 1
• VEGA ID
  OTTHUMG00000160448

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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