SBE13 hydrochloride

• Catalog number
  2847-50
• Price
  Please ask
• Size
  50 mg

• Alternative_name
  N-[[4-[(6-Chloro-3-pyridinyl)methoxy]-3-methoxyphenyl]methyl]-3,4-dimethoxybenzeneethanamine hydrochloride
• Description
  SBE13 HCl is a potent and selective PLK1 (Polo-like kinase 1) inhibitor (IC₅₀ = 200 pM). Displays activity against PLK2 and PLK3 at higher concentrations (IC₅₀ values of 66 µM and 875 nM, respectively). Has no effect on Aurora kinase A.
• CAS Number
  1052532-15-6
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₄H₂₇ClN₂O₄.HCl
• Molecular Weight
  479.4
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (>40 mg/ml) or H2O (~4 mg/ml with slight warming)
• Handling
  Protect from air and moisture
• Tag Line
  A potent and selective PLK1 (Polo-like kinase 1) inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• MDL Number
  MFCD20036266
• PubChem CID
  11948807
• PubChem CID Link
• SMILES
  COC1=C(C=C(C=C1)CCNCC2=CC(=C(C=C2)OCC3=CN=C(C=C3)Cl)OC)OC.Cl
• InChi
  InChI=1S/C24H27ClN2O4.ClH/c1-28-20-7-4-17(12-22(20)29-2)10-11-26-14-18-5-8-21(23(13-18)30-3)31-16-19-6-9-24(25)27-15-19;/h4-9,12-13,15,26H,10-11,14,16H2,1-3H3;1H
• InChi Key
  QBGSVDJLQQXEGG-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  SBE13   hydrochloride  
• Short name
  SBE13 hydrochloride
• Alternative name
  SBE13 hydrochloride

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