Lubiprostone
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Catalog numberB1319-1
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PricePlease ask
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Size1 mg
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Alternative_name(11a,15R)-11,15-Epoxy-16,16-difluoro-15-hydroxy-9-oxo-prostan-1-oic acid, Ru 0211, Spi 0211
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DescriptionLubiprostone is a bicyclic fatty acid metabolite analog of Prostaglandin E1 that activates ClC-2 and CFTR chloride channels. It has been suggested that lubiprostone opens CFTR or both CFTR and ClC-2 through interactions with the prostaglandin receptor EP4.
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CAS Number136790-76-6
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₂₀H₃₂F₂O₅
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Molecular Weight390.46
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO (~20 mg/ml)
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HandlingProtect from air and light
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Tag LineLubiprostone is a bicyclic fatty acid metabolite analog of Prostaglandin E1 that activates ClC-2 and CFTR chloride channels.
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life36 months
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PubChem CID157920
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SMILESCCCCC(C1(CCC2C(O1)CC(=O)C2CCCCCCC(=O)O)O)(F)F
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InChiInChI=1S/C20H32F2O5/c1-2-3-11-19(21,22)20(26)12-10-15-14(16(23)13-17(15)27-20)8-6-4-5-7-9-18(24)25/h14-15,17,26H,2-13H2,1H3,(H,24,25)/t14-,15-,17-,20-/m1/s1
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InChi KeyWGFOBBZOWHGYQH-MXHNKVEKSA-N
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MSDS AvailableYes
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Gene target
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Short nameLubiprostone
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Alternative nameLubiprostone
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