CXCL17, human recombinant

• Catalog number
  7345-50
• Price
  Please ask
• Size
  50 ug

• Synonyms
  Chemokine (C-X-C motif) ligand 17, Dcip1, DMC, MGC138300, UNQ473, VCC-1, VCC1
• Alternative_names
  Chemokine (C-X-C motif) ligand 17, Dcip1, DMC, MGC138300, UNQ473, VCC-1, VCC1
• Description
  Involved in the innate immune response
• Recombinant
  Yes
• Source
  E. coli
• Purity by SDS PAGE
  ≥85%
• Assay
  SDS-PAGE
• Molecular Weight
  13.7 kDa (119 aa, 22-119 aa + His Tag), confirmed by MALDI-TOF.
• Storage Temp
  -80°C
• Shipping
  Dry Ice
• Shelf Life
  12 months
• Concentration
  0.25 mg/ml
• Appearance
  Liquid
• Physical form description
  0.25 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea and 10% glycerol.
• Background Information
  Chemokine (C-X-C motif) ligand 17, also known as CXCL17, is a small cytokine belonging to the CXC chemokine family. CXCL17 is a 119 amino acid secreted protein that plays a role in angiogenesis. CXCL17 is expressed in skeletal muscle, trachea, lung, intestine and stomach, and is upregulated in duodenal mucosa of patients with acute cholera, as well as breast tumors. CXCL17 is considered a housekeeping chemokine for the movement of immature dendritic cells and non-activated blood monocytes into tissues, and is thought to be involved in the innate immune response. Recombinant human CXCL17 protein, fused to His-tag at N-terminus, was expressed in E.coli.
• Amino acid sequence
  MGSSHHHHHH SSGLVPRGSH MSSLNPGVAR GHRDRGQASR RWLQEGGQEC ECKDWFLRAP RRKFMTVSGL PKKQCPCDHF KGNVKKTRHQ RHHRKPNKHS RACQQFLKQC QLRSFALPL
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  CXCL17  
• Gene symbol
  CXCL17
• Short name
  CXCL17, recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  chemokine (C-X-C motif) ligand 17, H. sapiens Rec.
• Alternative technique
  rec
• Alternative to gene target
  chemokine (C-X-C motif) ligand 17, CXCL17 and IDBG-54351 and ENSG00000189377 and 284340, Extracellular, Cxcl17 and IDBG-157716 and ENSMUSG00000060188 and, CXCL17 and IDBG-638965 and ENSBTAG00000018652 and 788717

Gene info

• Identity
  HGNC:19232
• Gene
  CXCL17
• Long gene name
  C-X-C motif chemokine ligand 17
• Synonyms gene name
  • chemokine (C-X-C motif) ligand 17
• Synonyms
  • Dcip1
  • UNQ473
  • DMC
  • VCC1
• Locus
  19q13.2
• Discovery year
  2007-10-15
• Entrez gene record
  284340
• Pubmed identfication
  • 17201934
• Classification
  • Chemokine ligands
• VEGA ID
  OTTHUMG00000182817

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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