MIP-1γ/CCL9/10, murine recombinant

• Catalog number
  7174-50
• Price
  Please ask
• Size
  50 ug

• Synonyms
  Macrophage Inflammatory Protein-1γ, CCL9/10, MRP2, CCF18
• Alternative_names
  Macrophage Inflammatory Protein-1γ, CCL9/10, MRP2, CCF18
• Description
  Chemoattracts neutrophils and inhibits colony formation of bone marrow myeloid immature progenitors
• Recombinant
  Yes
• Source
  E. Coli
• Purity by SDS PAGE
  ≥98%
• Assay
  SDS-PAGE
• Endotoxin Level
  < 0.1 ng/ug of protein (
• Activity Specifications test method
  Determined by its ability to chemoattract human monocytes using a concentration range of 1.0-10.0 ng/ml.
• Biological activity
  Determined by its ability to chemoattract human monocytes using a concentration range of 1.0-10.0 ng/ml.
• Molecular Weight
  7.8 kDa
• Storage Temp
  -20°C
• Shipping
  Gel Pack
• Shelf Life
  12 months
• Appearance
  Lyophilized powder
• Physical form description
  Sterile filtered through a 0.2 micron filter. Lyophilized with no additives.
• Reconstitution Instructions
  Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
• Background Information
  MIP-1γ is a CC chemokine found in murine blood and a wide variety of murine tissues, with no known human homolog. MIP-1γ signals through the CCR1 receptor. MIP-1γ chemoattracts neutrophils and also inhibits colony formation of bone marrow myeloid immature progenitors. MIP-1γ contains six cysteines including the four highly conserved cysteine residues present in CC chemokines. Recombinant murine MIP-1γ is an 11.6 kDa protein containing 101 amino acid residues.
• Amino acid sequence
  QITHATETKE VQSSLKAQQG LEIEMFHMGF QDSSDCCLSY NSRIQCSRFI GYFPTSGGCT RPGIIFISKR GFQVCANPSD RRVQRCIERL EQNSQPRTYK Q
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  MIP-1γ/CCL9/10   murine  
• Gene symbol
  TNPO1, CCL3, CCL26, MAPKAP1, MIPEP, CCL23, RPTOR, CCL15, CCL4, CCL20
• Short name
  MIP-1γ/CCL9/10, murine recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Alternative name
  MIP-1γ/CCL9/10, murine Rec.
• Alternative technique
  rec

Gene info

• Identity
  HGNC:6401
• Gene
  TNPO1
• Long gene name
  transportin 1
• Synonyms gene
  • KPNB2
• Synonyms gene name
  • karyopherin (importin) beta 2
• Synonyms
  • MIP
  • TRN
  • IPO2
  • MIP1
• Synonyms name
  • importin 2
• GenBank acession
  • U70322
• Locus
  5q13.2
• Discovery year
  1997-04-21
• Entrez gene record
  3842
• Pubmed identfication
  • 8808633
  • 9144189
• RefSeq identity
  • NM_002270
• Classification
  • Importins
  • Armadillo like helical domain containing
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000100967

Gene info

• Identity
  HGNC:10627
• Gene
  CCL3
• Long gene name
  C-C motif chemokine ligand 3
• Synonyms gene
  • SCYA3
• Synonyms gene name
  • small inducible cytokine A3 (homologous to mouse Mip-1a)
  • chemokine (C-C motif) ligand 3
• Synonyms
  • G0S19-1
  • LD78ALPHA
  • MIP-1-alpha
• GenBank acession
  • M23178
• Locus
  17q12
• Discovery year
  1990-07-05
• Entrez gene record
  6348
• RefSeq identity
  • NM_002983
• Classification
  • Chemokine ligands
• VEGA ID
  OTTHUMG00000188413

Gene info

• Identity
  HGNC:10625
• Gene
  CCL26
• Long gene name
  C-C motif chemokine ligand 26
• Synonyms gene
  • SCYA26
• Synonyms gene name
  • small inducible cytokine subfamily A (Cys-Cys), member 26
  • chemokine (C-C motif) ligand 26
• Synonyms
  • MIP-4alpha
  • eotaxin-3
  • IMAC
  • MIP-4a
  • TSC-1
• Synonyms name
  • macrophage inflammatory protein 4-alpha
  • small inducible cytokine A26
  • CC chemokine IMAC
  • chemokine N1
  • thymic stroma chemokine-1
  • eotaxin-3
• GenBank acession
  • AF124601
• Locus
  7q11.23
• Discovery year
  1999-06-09
• Entrez gene record
  10344
• Pubmed identfication
  • 10373330
• RefSeq identity
  • NM_006072
• Classification
  • Chemokine ligands
• VEGA ID
  OTTHUMG00000130403

Gene info

• Identity
  HGNC:18752
• Gene
  MAPKAP1
• Long gene name
  MAPK associated protein 1
• Synonyms gene name
  • mitogen-activated protein kinase associated protein 1
• Synonyms
  • MGC2745
  • SIN1
  • MIP1
• Synonyms name
  • stress-activated protein kinase-interacting 1
• GenBank acession
  • M37191
• Locus
  9q33.3
• Discovery year
  2002-07-19
• Entrez gene record
  79109
• Pubmed identfication
  • 15363842
• Classification
  • MTOR complex 2
• VEGA ID
  OTTHUMG00000020683

Gene info

• Identity
  HGNC:7104
• Gene
  MIPEP
• Long gene name
  mitochondrial intermediate peptidase
• Synonyms
  • MIP
• Locus
  13q12.12
• Discovery year
  1996-10-30
• Entrez gene record
  4285
• Pubmed identfication
  • 9073519
  • 33669127
• Classification
  • M3 metallopeptidase family
• VEGA ID
  OTTHUMG00000016573

Gene info

• Identity
  HGNC:10622
• Gene
  CCL23
• Long gene name
  C-C motif chemokine ligand 23
• Synonyms gene
  • SCYA23
• Synonyms gene name
  • small inducible cytokine subfamily A (Cys-Cys), member 23
  • chemokine (C-C motif) ligand 23
• Synonyms
  • Ckb-8
  • MPIF-1
  • MIP-3
  • CKb8
• GenBank acession
  • U58913
• Locus
  17q12
• Discovery year
  1997-11-14
• Entrez gene record
  6368
• Pubmed identfication
  • 9104803
  • 10409433
• RefSeq identity
  • NM_005064
  • NM_145898
• Classification
  • Chemokine ligands
• VEGA ID
  OTTHUMG00000188409

Gene info

• Identity
  HGNC:30287
• Gene
  RPTOR
• Long gene name
  regulatory associated protein of MTOR complex 1
• Synonyms gene name
  • regulatory associated protein of MTOR, complex 1
• Synonyms
  • KOG1
  • Mip1
  • KIAA1303
  • raptor
• Synonyms name
  • regulatory associated protein of mTOR
• Locus
  17q25.3
• Discovery year
  2009-05-29
• Entrez gene record
  57521
• Pubmed identfication
  • 10718198
  • 12150926
• RefSeq identity
  • NM_020761
• Classification
  • WD repeat domain containing
  • MTOR complex 1
  • Armadillo like helical domain containing
• VEGA ID
  OTTHUMG00000177622

Gene info

• Identity
  HGNC:10613
• Gene
  CCL15
• Long gene name
  C-C motif chemokine ligand 15
• Synonyms gene
  • SCYA15
• Synonyms gene name
  • small inducible cytokine subfamily A (Cys-Cys), member 15
  • chemokine (C-C motif) ligand 15
• Synonyms
  • HCC-2
  • NCC-3
  • SCYL3
  • MIP-5
  • Lkn-1
  • MIP-1d
  • HMRP-2B
• Synonyms name
  • leukotactin 1
  • CC chemokine 3
  • macrophage inflammatory protein 5
  • chemokine CC-2
  • MIP-1 delta
• GenBank acession
  • AF031587
• Locus
  17q12
• Discovery year
  1997-02-11
• Entrez gene record
  6359
• Pubmed identfication
  • 8661057
• RefSeq identity
  • NM_004167
• Classification
  • Chemokine ligands
• VEGA ID
  OTTHUMG00000188406

Gene info

• Identity
  HGNC:10630
• Gene
  CCL4
• Long gene name
  C-C motif chemokine ligand 4
• Synonyms gene
  • LAG1
  • SCYA4
• Synonyms gene name
  • small inducible cytokine A4 (homologous to mouse Mip-1b)
  • chemokine (C-C motif) ligand 4
• Synonyms
  • MIP-1-beta
  • Act-2
  • AT744.1
• GenBank acession
  • M23502
• Locus
  17q12
• Discovery year
  1990-07-05
• Entrez gene record
  6351
• Pubmed identfication
  • 1972563
• RefSeq identity
  • NM_002984
• Classification
  • Chemokine ligands
• VEGA ID
  OTTHUMG00000188414

Gene info

• Identity
  HGNC:10619
• Gene
  CCL20
• Long gene name
  C-C motif chemokine ligand 20
• Synonyms gene
  • SCYA20
• Synonyms gene name
  • small inducible cytokine subfamily A (Cys-Cys), member 20
  • chemokine (C-C motif) ligand 20
• Synonyms
  • LARC
  • MIP-3a
  • exodus-1
  • ST38
  • CKb4
• GenBank acession
  • D86955
• Locus
  2q36.3
• Discovery year
  1997-02-10
• Entrez gene record
  6364
• Pubmed identfication
  • 9038201
  • 11352563
• RefSeq identity
  • NM_004591
• Classification
  • Chemokine ligands
• VEGA ID
  OTTHUMG00000133189

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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