VER-155008

  • Catalog number
    B2413-5
  • Price
    Please ask
  • Size
    5 mg
  • Alternative_name
    5'-O-[(4-Cyanophenyl)methyl]-8-[[(3,4-dichlorophenyl)methyl]amino]-adenosine
  • Description
    VER-155008 is a potent heat shock protein 70 (Hsp70) inhibitor (IC₅₀ = 0.5 μM). Inhibits cell proliferation of multiple human tumor cell lines in vitro. Also binds Hsc70 and Grp78 and displays selectivity against Hsp90β (IC₅₀ >200 μM for Hsp90β). Displays potent anticancer activity.
  • CAS Number
    1134156-31-2
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₂₅H₂₃Cl₂N₇O₄
  • Molecular Weight
    556.4
  • Cell Permeable
    True
  • Purity
    ≥98% by HPLC
  • Solubilities
    Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
  • Handling
    Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
  • Tag Line
    A Hsp70 inhibitor
  • Storage Condition
    -20ºC
  • Shipping Condition
    Gel Pack
  • Shelf Life
    36 months
  • PubChem CID
    25195348
  • SMILES
    C1=CC(=CC=C1COCC2C(C(C(O2)N3C4=C(C(=NC=N4)N)N=C3NCC5=CC(=C(C=C5)Cl)Cl)O)O)C#N
  • InChi
    InChI=1S/C25H23Cl2N7O4/c26-16-6-5-15(7-17(16)27)9-30-25-33-19-22(29)31-12-32-23(19)34(25)24-21(36)20(35)18(38-24)11-37-10-14-3-1-13(8-28)2-4-14/h1-7,12,18,20-21,24,35-36H,9-11H2,(H,30,33)(H2,29,31,32)/t18-,20-,21-,24-/m1/s1
  • InChi Key
    ZXGGCBQORXDVTE-UMCMBGNQSA-N
  • MSDS Available
    True
  • Gene target
  • Short name
    VER-155008
  • Alternative name
    VER-155008
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