VER-155008
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Catalog numberB2413-5
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PricePlease ask
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Size5 mg
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Alternative_name5'-O-[(4-Cyanophenyl)methyl]-8-[[(3,4-dichlorophenyl)methyl]amino]-adenosine
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DescriptionVER-155008 is a potent heat shock protein 70 (Hsp70) inhibitor (IC₅₀ = 0.5 μM). Inhibits cell proliferation of multiple human tumor cell lines in vitro. Also binds Hsc70 and Grp78 and displays selectivity against Hsp90β (IC₅₀ >200 μM for Hsp90β). Displays potent anticancer activity.
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CAS Number1134156-31-2
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₂₅H₂₃Cl₂N₇O₄
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Molecular Weight556.4
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Cell PermeableTrue
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Purity≥98% by HPLC
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SolubilitiesDo not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
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HandlingDo not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
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Tag LineA Hsp70 inhibitor
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Storage Condition-20ºC
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Shipping ConditionGel Pack
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Shelf Life36 months
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PubChem CID25195348
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SMILESC1=CC(=CC=C1COCC2C(C(C(O2)N3C4=C(C(=NC=N4)N)N=C3NCC5=CC(=C(C=C5)Cl)Cl)O)O)C#N
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InChiInChI=1S/C25H23Cl2N7O4/c26-16-6-5-15(7-17(16)27)9-30-25-33-19-22(29)31-12-32-23(19)34(25)24-21(36)20(35)18(38-24)11-37-10-14-3-1-13(8-28)2-4-14/h1-7,12,18,20-21,24,35-36H,9-11H2,(H,30,33)(H2,29,31,32)/t18-,20-,21-,24-/m1/s1
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InChi KeyZXGGCBQORXDVTE-UMCMBGNQSA-N
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MSDS AvailableTrue
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Gene target
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Short nameVER-155008
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Alternative nameVER-155008
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