TRIB1 Antibody

• Catalog number
  6967-100
• Price
  Please ask
• Size
  100 µl

• Antibody Target
  TRIB1
• Target Alternative Name
  Tribbles homolog 1, TRB-1, G-protein-coupled receptor-induced gene 2 protein, GIG-2, SKIP1, TRIB1
• Antibody Type
  Polyclonal
• Species Reactivities
  Human. Predicted cross reactivity with mouse samples
• Immunogen Sequence
  This TRIB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 341-370 amino acids from the C-terminal region of human TRIB1
• Accession
  Q96RU8
• Gene Id
  10221
• Appearance
  Colorless liquid
• Form
  Liquid
• Formulation
  In PBS with 0.09% (W/V) sodium azide
• Purification
  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Application
  Western blot
• Positive Control
  Western Blot:T47D cell line lysate (35 µg/lane)
• Application And Usages
  WB: ~1:1000
• Description
  TRIB1 antibody, also called gprotein coupled receptor induced, skip1, gig2, c8fwATP, functions in protein binding, protein kinase inhibitor activity, and protein serine/threonine kinase activities. Overexpression of TRIB1 in HeLa cells repressed the basal activity of the IL8 promoter by inhibiting AP1 activity. Overexpression of TRIB1 inhibited oncogenic Ras -driven AP1 activation and MEKK1-mediated AP1 activation. ERK activation was enhanced by TRIB1. Coimmunoprecipitation and yeast 2-hybrid assays showed that MEK1 interacted with both TRIB1 and TRIB3, and MKK4 interacted specifically with TRIB1. Cotransfection of MKK4 enhanced the level of TRIB1, indicating that the TRIB-MAPKK interaction stabilized TRIB1
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Dot Blot Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TRIB1  
• Gene symbol
  TRIB1
• Short name
  TRIB1 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  tribbles homolog 1 (Drosophila) (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  tribbles homolog 1 (Drosophila), C8FW and GIG-2 and GIG2 and SKIP1 and TRB-1 and TRB1, TRIB1 and IDBG-35403 and ENSG00000173334 and 10221, transferase activity, nuclei, Trib1 and IDBG-144324 and ENSMUSG00000032501 and 211770, TRIB1 and IDBG-644151 and ENSBTAG00000023179 and 521857

Gene info

• Identity
  HGNC:16891
• Gene
  TRIB1
• Long gene name
  tribbles pseudokinase 1
• Synonyms gene name
  • tribbles homolog 1 (Drosophila)
• Synonyms
  • C8FW
  • GIG2
  • TRB1
• GenBank acession
  • AF205437
• Locus
  8q24.13
• Discovery year
  2004-05-10
• Entrez gene record
  10221
• Pubmed identfication
  • 9342215
  • 16715410
• RefSeq identity
  • NM_025195
• VEGA ID
  OTTHUMG00000165007

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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