CDH18 Antibody, ALEXA FLUOR 350

• Catalog number
  bs-11073R-A350
• Price
  Please ask
• Size
  100ul

• Long name
  CDH18 Polyclonal Antibody, ALEXA FLUOR 350 Conjugated
• Also known as
  Anti-CDH18 PAb ALEXA FLUOR 350
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 350
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  CDH18
• Specificity
  This is a highly specific antibody against CDH18.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Subcellular location
  Extracellular
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CDH18
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  The cadherins are a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding events that are critical to the maintenance of cell structure and morphogenesis. EY-cadherin, also known as CDH18 (cadherin 18), CDH14 (cadherin 14), CDH24 or CDH14L, is a 790 amino acid single-pass type I membrane protein that contains five cadherin domains. One of several members of the cadherin superfamily, EY-cadherin functions as a type II classical cadherin that is expressed specifically in the central nervous system (CNS), where it plays a role in cell-cell binding events. Specifically, EY-cadherin is thought to be involved in axon guidance and outgrowth, as well as synaptic adhesion within the CNS. EY-cadherin contains a highly conserved C-terminal domain characteristic of all cadherins, but lacks the HAV cell adhesion sequence that is specific to type I cadherins. The gene encoding EY-cadherin is located within a region on chromosome five that is commonly deleted in carcinomas, implicating EY-cadherin as a potential tumor suppressor.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  343nm/442nm
• Synonyms
  CAD18_HUMAN; Cadherin 14; Cadherin14; Cadherin 18; Cadherin18; Cadherin 18, type 2; Cadherin-14; Cadherin-18; CDH14; CDH14L; CDH18; CDH24; EY CADHERIN.
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 350
• French translation
  anticorps

• Gene target
  CDH18  
• Gene symbol
  CDH18-AS1, CDH18
• Short name
  Anti-CDH18
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 350
• Alternative name
  CDH18 Polyclonal Antibody, ALEXA FLUOR 350
• Alternative technique
  antibodies
• Alternative to gene target
  cadherin 18, type 2, CDH14 and CDH14L and CDH24, CDH18 and IDBG-13642 and ENSG00000145526 and 1016, calcium ion binding, Plasma membranes, Cdh18 and IDBG-130778 and ENSMUSG00000040420 and 320865, CDH18 and IDBG-631065 and ENSBTAG00000037844 and 512080

Gene info

• Identity
  HGNC:53088
• Gene
  CDH18-AS1
• Long gene name
  CDH18 antisense RNA 1
• Locus
  5p14.3
• Discovery year
  2017-02-08
• Entrez gene record
  102725105
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:1757
• Gene
  CDH18
• Long gene name
  cadherin 18
• Synonyms gene name
  • cadherin 18, type 2
• Synonyms
  • CDH14
  • EY-CADHERIN
• GenBank acession
  • U59325
• Locus
  5p14.3
• Discovery year
  1997-06-25
• Entrez gene record
  1016
• Pubmed identfication
  • 9030594
  • 10191097
• RefSeq identity
  • NM_004934
• Classification
  • Type II classical cadherins
• VEGA ID
  OTTHUMG00000090578

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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