SU-5402
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Catalog number1645-05
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PricePlease ask
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Size500 ug
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Alternative_name2-[(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl]-4-meth yl-1H-pyrrole-3-propanoic acid
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DescriptionA potent and selective inhibitor of fibroblast growth factor receptor (FGFR) (IC₅₀ = 0.03 µM for FGFR1) and vascular endothelial growth factor receptors (VEGFR) (IC₅₀ = 0.02 µM for VEGFR2). In addition, integrin β4-induced differentiation of neural stem cells was attenuated by SU 5402.
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CAS Number215543-92-3
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₁₇H₁₆N₂O₃
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Molecular Weight296.32
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Cell PermeableNo
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Purity≥97% by HPLC
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SolubilitiesDMSO (100 mM) )
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HandlingProtect from air and light
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Tag LineA FGFR inhibitor
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life24 months
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MDL NumberMFCD08235144
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PubChem CID5289418
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SMILESCC1=CNC(=C1CCC(=O)O)C=C2C3=CC=CC=C3NC2=O
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InChiInChI=1S/C17H16N2O3/c1-10-9-18-15(11(10)6-7-16(20)21)8-13-12-4-2-3-5-14(12)19-17(13)22/h2-5,8-9,18H,6-7H2,1H3,(H,19,22)(H,20,21)/b13-8-
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InChi KeyJNDVEAXZWJIOKB-JYRVWZFOSA-N
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MSDS AvailableYes
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Gene target
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Short nameSU-5402
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Alternative nameSU-5402
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