SU-5402

  • Catalog number
    1645-05
  • Price
    Please ask
  • Size
    500 ug
  • Alternative_name
    2-[(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl]-4-meth yl-1H-pyrrole-3-propanoic acid
  • Description
    A potent and selective inhibitor of fibroblast growth factor receptor (FGFR) (IC₅₀ = 0.03 µM for FGFR1) and vascular endothelial growth factor receptors (VEGFR) (IC₅₀ = 0.02 µM for VEGFR2). In addition, integrin β4-induced differentiation of neural stem cells was attenuated by SU 5402.
  • CAS Number
    215543-92-3
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₁₇H₁₆N₂O₃
  • Molecular Weight
    296.32
  • Cell Permeable
    No
  • Purity
    ≥97% by HPLC
  • Solubilities
    DMSO (100 mM) )
  • Handling
    Protect from air and light
  • Tag Line
    A FGFR inhibitor
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    24 months
  • MDL Number
    MFCD08235144
  • PubChem CID
    5289418
  • SMILES
    CC1=CNC(=C1CCC(=O)O)C=C2C3=CC=CC=C3NC2=O
  • InChi
    InChI=1S/C17H16N2O3/c1-10-9-18-15(11(10)6-7-16(20)21)8-13-12-4-2-3-5-14(12)19-17(13)22/h2-5,8-9,18H,6-7H2,1H3,(H,19,22)(H,20,21)/b13-8-
  • InChi Key
    JNDVEAXZWJIOKB-JYRVWZFOSA-N
  • MSDS Available
    Yes
  • Gene target
    SU-5402  
  • Short name
    SU-5402
  • Alternative name
    SU-5402
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