Dimethyl Fumarate

• Catalog number
  9660-500
• Price
  Please ask
• Size
  500 mg

• Alternative_name
  2(E)-Butenedioic acid 1,4-dimethyl ester; DMF
• Description
  Dimethyl fumarate is an anti-inflammatory agent. It effectively blocks NF-κB activity in multiple breast cancer cell lines and abrogates NF-κB-dependent mammosphere formation, indicating that DMF has anti-cancer stem cell properties. In addition, DMF inhibits cell proliferation and significantly impairs xenograft tumor growth. DMF also prevents p65 nuclear translocation and attenuates its DNA binding activity but has no effect on upstream proteins in the NF-κB pathway.
• CAS Number
  624-49-7
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₆H₈O₄
• Molecular Weight
  144.13
• Cell Permeable
  Yes
• Purity
  ≥98% by GC
• Solubilities
  DMSO (>15 mg/ml) or EtOH (>5 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  An anti-inflammatory agent and NF-κB activity blocker
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• MDL Number
  MFCD00064438
• PubChem CID
  637568
• PubChem CID Link
• SMILES
  COC(=O)/C=C/C(=O)OC
• InChi
  InChI=1S/C6H8O4/c1-9-5(7)3-4-6(8)10-2/h3-4H,1-2H3/b4-3+
• InChi Key
  LDCRTTXIJACKKU-ONEGZZNKSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Dimethyl   Fumarate  
• Short name
  Dimethyl Fumarate
• Alternative name
  Dimethyl Fumarate

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