MALT1 (MALT-Lymphoma Marker) Mouse Monoclonal Antibody

• Catalog number
  MBS438138
• Price
  Please ask
• Size
  0.02 mg (With BSA & Azide at 0.2mg/mL)

• Products_type
  Antibody
• Products_short_name
  [MALT1 (MALT-Lymphoma Marker)]
• Products_name_syn
  [Caspase-like protein, MALT lymphoma-associated translocation, MLT1, Mucosa-associated lymphoid tissue lymphoma translocation protein 1, Paracaspase]
• Other_names
  [mucosa-associated lymphoid tissue lymphoma translocation protein 1 isoform a; Mucosa-associated lymphoid tissue lymphoma translocation protein 1; mucosa-associated lymphoid tissue lymphoma translocation protein 1; MALT1 paracaspase; MALT lymphoma-associated translocation; Paracaspase]
• Products_gene_name
  [MALT1]
• Other_gene_names
  [MALT1; MALT1; MLT; MLT1; IMD12; PCASP1; MLT]
• Clonality
  Monoclonal
• Reactivity
  Human
• Specificity
  Mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1) is found in extranodal low-grade B cell lymphomas. MALT1 encodes two Ig-like C2-type domains and fuses with an API2 gene, which is highly expressed in adult lymphoid tissue. The translocation of this MALT1 gene, which maps to human chromosome 18q21, and the apoptosis-inhibiting API2 gene results in an increased development of MALT lymphomas and apoptosis inhibition. Sites at which this API2-MALT1 (11;18)(q21;q21) translocation commonly occurs are within human lung and kidney tissue. MALT lymphoma expresses nuclear Bcl10, which mediates the oligomerization and activation of a MALT1 caspase-like domain. MALT1 mRNA is found in pre-B cells, mature B cells and plasma cells.
• Form
  200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Storage_stability
  Antibody with azide - store at 2 to 8 degree C. Antibody without azide - store at -20 to -80 degree C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
• Tested_application
  Western Blot (WB), Immunohistochemistry (IHC) Formalin
• Properties
  If you buy Antibodies supplied by MyBioSource they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus
• French translation
  anticorps

• Gene target
  MALT1   MALT-Lymphoma   Monoclonal  
• Gene symbol
  MALT1-AS1, MALT1
• Short name
  MALT1 (MALT-Lymphoma ) Mouse Monoclonal Antibody
• Technique
  Mouse monoclonal, Antibody, Mouse, antibodies against human proteins, antibodies for, Component cell markers and DNA bp. markers are genetic markers er genes or DNA sequences with a known location on a chromosome that can be used to identify individuals or species. Protein markers in kDA. Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
• Host
  Mouse, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
• Isotype
  IgG1, kappa
• Species
  Mouse, Mouses
• Alternative name
  mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT-Lymphoma detection labelled) Mouse monoclonal (antibody to-)
• Alternative technique
  antibodies, murine
• Alternative to gene target
  mucosa associated lymphoid tissue lymphoma translocation gene 1, IMD12 and MLT and MLT1, MALT1 and IDBG-3930 and ENSG00000172175 and 10892, protein self-association, nuclei, Malt1 and IDBG-154592 and ENSMUSG00000032688 and 240354, MALT1 and IDBG-644866 and ENSBTAG00000027916 and 504994

Gene info

• Identity
  HGNC:55306
• Gene
  MALT1-AS1
• Long gene name
  MALT1 antisense RNA 1
• Locus
  18q21.32
• Discovery year
  2020-10-16
• Entrez gene record
  101927322
• RefSeq identity
  • NR_164150
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:6819
• Gene
  MALT1
• Long gene name
  MALT1 paracaspase
• Synonyms gene
  • MLT
• Synonyms gene name
  • mucosa associated lymphoid tissue lymphoma translocation gene 1
• Synonyms
  • PCASP1
• Synonyms name
  • MALT1 protease
  • paracaspase 1
• Locus
  18q21.32
• Discovery year
  1999-08-02
• Entrez gene record
  10892
• Pubmed identfication
  • 10339464
  • 10406266
  • 10523859
  • 11090634
  • 26377317
• RefSeq identity
  • NM_006785
• Classification
  • Immunoglobulin like domain containing
  • CBM complex
• VEGA ID
  OTTHUMG00000132761
• Locus Specific Databases
  • LRG_1221

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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