Lomitapide

• Catalog number
  2876-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  N-(2,2,2-trifluoroethyl)-9-(4-(4-(4'-(trifluoromethyl)-[1,1'-biphenyl]-2-ylcarboxamido)piperidin-1-yl)butyl)-9H-fluorene-9-carboxamide; BMS201038; AEGR773
• Description
  Lomitapide is a small molecule that lowers total cholesterol levels by inhibiting microsomal triglyceride transfer protein (MTTP) and preventing the assembly of apoB-containing lipoproteins and VLDL synthesis. Lomitapide is also a substrate and inhibitor of CYP3A4.
• CAS Number
  182431-12-5
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₃₉H₃₇F₆N₃O₂
• Molecular Weight
  693.72
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (~ 5 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A microsomal triglyceride transfer protein (MTP) inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  9853053
• PubChem CID Link
• SMILES
  C1CN(CCC1NC(=O)C2=CC=CC=C2C3=CC=C(C=C3)C(F)(F)F)CCCCC4(C5=CC=CC=C5C6=CC=CC=C64)C(=O)NCC(F)(F)F
• InChi
  InChI=1S/C39H37F6N3O2/c40-38(41,42)25-46-36(50)37(33-13-5-3-10-30(33)31-11-4-6-14-34(31)37)21-7-8-22-48-23-19-28(20-24-48)47-35(49)32-12-2-1-9-29(32)26-15-17-27(18-16-26)39(43,44)45/h1-6,9-18,28H,7-8,19-25H2,(H,46,50)(H,47,49)
• InChi Key
  MBBCVAKAJPKAKM-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Lomitapide  
• Short name
  Lomitapide
• Alternative name
  Lomitapide

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