GST Inhibitor-2 (Ethacrynic acid))

Alternative_name

GST Inhibitor-2, Ethacrynic acid
Description

An effective Glutathione S-transferase(GST) inhibitor at 2-100 µM
CAS Number

58-54-8
Structure Available

Yes
Salt Form

No
Molecular Formula

C₁₃H₁₂CI₂O₄
Molecular Weight

303.14
Cell Permeable

Yes
Purity

≥99%
Solubilities

EtOH (50 mg/ml)
Handling

Protect from light and moisture
Tag Line

A GST inhibitor
Storage Condition

RT
Shipping Condition

gel pack
Shelf Life

24months
MDL Number

MFCD00056693
PubChem CID

3278
PubChem CID Link
SMILES

CCC(=C)C(=O)C1=C(C(=C(C=C1)OCC(=O)O)Cl)Cl
InChi

InChI=1S/C13H12Cl2O4/c1-3-7(2)13(18)8-4-5-9(12(15)11(8)14)19-6-10(16)17/h4-5H,2-3,6H2,1H3,(H,16,17)
InChi Key

AVOLMBLBETYQHX-UHFFFAOYSA-N
Data Sheet Link
MSDS Available

Yes
Additional description

Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.