P21 Antibody, HRP Conjugated
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Catalog numberbs-10129R-HRP
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PricePlease ask
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Size0.1ml
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Long nameP21 Polyclonal Antibody, HRP Conjugated
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CategoryConjugated Primary Antibodies
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ConjugationHRP
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Host OrganismRabbit (Oryctolagus cuniculus)
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Target AntigenP21
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SpecificityThis is a highly specific antibody against P21.
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ModificationUnmodified
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Modification siteNone
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ClonalityPolyclonal
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ClonePolyclonal antibody
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Concentration1ug per 1ul
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Immunogen_range13-41/164
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Subcellular locationCytoplasm, Nucleus
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SourceKLH conjugated synthetic peptide derived from human P21
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Gene ID number1026
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Swiss ProtP38936
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Tested applicationsWB, IHC-P
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Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500)
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CrossreactivityHuman, Mouse, Rat
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Crossreactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Antigen backgroundMay be the important intermediate by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% Gentamicin. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
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Excitation EmissionN/A
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SynonymsP21; CIP1; SDI1; WAF1; CAP2; CDKN1; MDA-6; p21CIP1; Cyclin-dependent kinase inhibitor 1; CDK-interacting protein 1; Melanoma differentiation-associated protein 6; CDKN1A; MDA6; PIC1
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PropertiesIf you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. HRP conjugates are often primary rabbit polyclonal antibodies couples to the enzyme horseradish peroxidase (HRP), found in the roots of horseradish. Also monoclonal HRP conjugates are often used for Western Blot.
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Additional conjugationHRP Conjugated
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French translationanticorps
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Gene target
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Gene symbolTP53COR1, TCEAL1, RPL21P26, NSG1, H3P16
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Short nameAnti-P21
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TechniqueAntibody, antibodies against human proteins, antibodies for, antibody Conjugates
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IsotypeImmunoglobulin G (IgG)
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LabelHRP
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Alternative nameAnti-P21 PAb HRP
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nametumor protein p53 pathway corepressor 1
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Synonyms gene name
- tumor protein p53 pathway corepressor 1 (non-protein coding)
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Synonyms
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GenBank acession
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Locus
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Discovery year2015-03-25
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Entrez gene record
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Pubmed identfication
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Classification
- Long non-coding RNAs with non-systematic symbols
Gene info
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Identity
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Gene
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Long gene nametranscription elongation factor A like 1
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Synonyms gene name
- transcription elongation factor A (SII)-like 1
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-09-21
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Transcription elongation factor A like family
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameribosomal protein L21 pseudogene 26
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Locus
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Discovery year2009-03-06
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Entrez gene record
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Pubmed identfication
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RefSeq identity
Gene info
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Identity
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Gene
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Long gene nameneuronal vesicle trafficking associated 1
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Synonyms
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Synonyms name
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Locus
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Discovery year2017-06-23
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Entrez gene record
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Pubmed identfication
Gene info
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Identity
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Gene
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Long gene nameH3 histone pseudogene 16
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Synonyms gene
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Synonyms gene name
- H3 histone, family 3A, pseudogene 6
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Synonyms
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Locus
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Discovery year2011-09-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data