LLL12
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Catalog number1792-5
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PricePlease ask
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Size5 mg
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Alternative_name5-Hydroxy-9,10-dioxo-9,10-dihydroanthracene-1-sulfonamide
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DescriptionA Stat3 phosphorylation inhibitor. LLL12 inhibits STAT3 phosphorylation (Tyr705) and STAT3 activities and down-regulates STAT3 downstream targets; inhibits proliferation, colony formation, and cell migration and induces apoptosis in various human breast and pancreatic cancer cells as well as in glioblastoma cells. LLL12 has minimal apoptotic effects on normal human cells.
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₁₄H₉NO₅S
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Molecular Weight303.29
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Cell PermeableYes
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Purity≥95% by ¹H NMR
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SolubilitiesDMSO
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HandlingProtect from air and light
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Tag LineA Stat3 phosphorylation inhibitor
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life48 months
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SMILESN/A
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InChiN/A
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InChi KeyN/A
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MSDS AvailableYes
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Gene target
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Short nameLLL12
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Alternative nameLLL12
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