LLL12

  • Catalog number
    1792-5
  • Price
    Please ask
  • Size
    5 mg
  • Alternative_name
    5-Hydroxy-9,10-dioxo-9,10-dihydroanthracene-1-sulfonamide
  • Description
    A Stat3 phosphorylation inhibitor. LLL12 inhibits STAT3 phosphorylation (Tyr705) and STAT3 activities and down-regulates STAT3 downstream targets; inhibits proliferation, colony formation, and cell migration and induces apoptosis in various human breast and pancreatic cancer cells as well as in glioblastoma cells. LLL12 has minimal apoptotic effects on normal human cells.
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₁₄H₉NO₅S
  • Molecular Weight
    303.29
  • Cell Permeable
    Yes
  • Purity
    ≥95% by ¹H NMR
  • Solubilities
    DMSO
  • Handling
    Protect from air and light
  • Tag Line
    A Stat3 phosphorylation inhibitor
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    48 months
  • SMILES
    N/A
  • InChi
    N/A
  • InChi Key
    N/A
  • MSDS Available
    Yes
  • Gene target
    LLL12  
  • Short name
    LLL12
  • Alternative name
    LLL12
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