EED Antibody

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• Catalog number
  F53258-0.4ML
• Price:

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• Size
  0.4 ml

# #

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  EED
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, ELISA
• Recommended dilutions
  Western blot: 1:1000
• Notes
  Titration of the EED antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This EED antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  O75530
• Purity
  Antigen affinity
• Description
  Polycomb protein EED is a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin β7, immunodeficiency virus type 1 (HIV-1) MA protein, and histone deacetylase proteins. This protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function. Two transcript variants encoding distinct isoforms have been identified for this gene. [Wiki]
• Immunogen
  This EED antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 38-72 amino acids from the N-terminal region of human EED.
• Storage
  Aliquot the EED antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

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• Gene target
  EED  
• Gene symbol
  EED
• Short name
  Anti-EED
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to EED
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:3188
• Gene
  EED
• Long gene name
  embryonic ectoderm development
• Synonyms
  • WAIT-1
  • HEED
• Synonyms name
  • WD protein associating with integrin cytoplasmic tails 1
• GenBank acession
  • AF078933
• Locus
  11q14.2
• Discovery year
  1998-12-09
• Entrez gene record
  8726
• Pubmed identfication
  • 9765275
  • 9806832
• RefSeq identity
  • NM_003797
• Classification
  • WD repeat domain containing
  • MicroRNA protein coding host genes
  • Polycomb repressive complex 2
• VEGA ID
  OTTHUMG00000167209

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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