MUC1 Polyclonal Antibody

• Catalog number
  CAC07111
• Price
  Please ask
• Size
  50 μg

• Other name
  PUM,MUC1,Breast carcinoma-associated antigen DF3 Carcinoma-associated mucin,Episialin,H23AG,Krebs von den Lungen-6,KL-6,PEMT,Peanut-reactive urinary mucin,PUM,Polymorphic epithelial mucin,PEM,Tumor-associated epithelial membrane antigen,EMA,Tumor-associa
• Immunogen
  Recombinant human Mucin-1 protein (24-273AA)
• Verified reactivity
  human
• Verified applications
  ELISA,IHC,IF. Recommended dilution:IHC:1:20-1:200,IF:1:50-1:200
• Raised in
  Rabbit
• Clonality
  Polyclonal
• Protein number
  P15941
• Gene number
  Please refer to GenBank
• NCBI number
  Please refer to NCBI
• Purity
  Caprylic Acid Ammonium Sulfate Precipitation Purified
• Storage recommendation
  Aliquot and store at -20°C. Minimize freezing and thawing.
• Use before
  1 year
• Shipping requirements
  Blue ice
• Estimated production time
  3-7 business days
• Supplementary information
  The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. Ref.26 Ref.37 Ref.40 Ref.45 Ref.46 Ref.49 Ref.52 Ref.53 Ref.56.The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of TP53 and represses TP53 activity.
• Notes
  For research use only. Not for diagnostic procedures.
• Hyperlink
• Properties
  If you buy Antibodies supplied by bioma they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
• French translation
  anticorps

• Gene target
  MUC1  
• Gene symbol
  MUC1
• Short name
  MUC1 Polyclonal Antibody
• Technique
  Polyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Label
  Unconjugated
• Alternative name
  MUC1 polyclonal (antibody to-)
• Alternative technique
  polyclonals, antibodies

Gene info

• Identity
  HGNC:7508
• Gene
  MUC1
• Long gene name
  mucin 1, cell surface associated
• Synonyms gene
  • PUM
  • MCKD1
• Synonyms gene name
  • mucin 1, transmembrane
  • medullary cystic kidney disease 1 (autosomal dominant)
• Synonyms
  • CD227
  • PEM
  • ADMCKD
  • ADMCKD1
  • MCKD
  • MCD
  • KL-6
  • EMA
  • Ca15-3
• Synonyms name
  • epithelial membrane antigen
• GenBank acession
  • J05581
• Locus
  1q22
• Discovery year
  1986-01-01
• Entrez gene record
  4582
• Pubmed identfication
  • 1697589
  • 23396133
• RefSeq identity
  • NM_002456
• Classification
  • CD molecules
  • Mucins
• VEGA ID
  OTTHUMG00000035681

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products