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Azidothymidine

Azidothymidine is available 4 times from Biovision labs

B1113-10 | Azidothymidine size: 2X10 mg | 317.69 USD

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B1113-50 | Azidothymidine size: 50 mg | 425.48 USD

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B1113-50 | Azidothymidine for cell activation size: 50 mg | 334.71 USD

Catalog number B1113-50
Supplier Biovision
Price334.71 USD
Size 50 mg
Additional description For cells, cell lines and tissues in culture till half confluency.
Short name Azidothymidine for activation
Technique activation
Alternative name Azidothymidine to measure cellular activation
Tissue cell
Additional information
Product images
    #0#.jpegAzidothymidine

B1113-10 | Azidothymidine for cell activation size: 10 mg | 137.29 USD

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Alternate Name/Synonyms 3'-Azido-3'-deoxythymidine; AZT; Zidovudine
Appearance White solid
Formulation N/A
CAS Number 30516-87-1
Peptide sequence N/A
Molecular Formula C₁₀H₁₃N₅O₄
Molecular Weight 267.24
Purity ≥98% by HPLC
Solubility/Reconstitution Instructions DMSO (>25 mg/ml) or H2O (>10 mg/ml)
Handling Protect from air and moisture
Tagline A nucleoside reverse transcriptase inhibitor and homology directed repair (HDR) blocker
Storage Temp. -20°C
Shipping Conditions gel pack
Shelf Life 36 months
MDL Number MFCD00006536
PubChem CID 35370
Category Biochemicals
Description Azidothymidine is a nucleoside reverse transcriptase inhibitor that, following triphosphorylation by thymidine kinase, potently blocks replication of HIV (EC₅₀ = 3 nM) with low cytotoxicity (CC₅₀ > 5 μM). Displays 100-fold selectivity for HIV reverse transcriptase over DNA polymerase α. Suppresses HIV-1 replication and enhances cell viability in HIV-1 infected T cells. Antiretroviral agent. Also decreases CRISPR-mediated homology directed repair (HDR) efficiency.
CAS number 30516-87-1
Molecular weight 267.24
Other name 3'-Azido-3'-deoxythymidine; AZT; Zidovudine
Molecular formula C₁₀H₁₃N₅O₄
Physical appearance White solid
Supplied with N/A
Is this a salt? No
Is it cell-permeable? Yes
Purification ≥98% by HPLC
Reconstitute instructions DMSO (>25 mg/ml) or H2O (>10 mg/ml)
Storage condition -20°C
Shipping condition gel pack
Maximum time for storage 36 months
Storage instructions Protect from air and moisture
Alternative technique blots
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