CZC24832
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Catalog numberB1676-5
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PricePlease ask
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Size5 mg
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Alternative_nameCZC24832; CZC 24832; CZC-24832; 5-(2-amino-8-fluoro-[1,2,4]triazolo[1,5-a]pyridin-6-yl)-N-tert-butylpyridine-3-sulfonamide
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DescriptionCZC24832 is a selective inhibitor of PI 3-kinase γ (IC50 = 1.0 μM in a PI 3-Kγ-dependent fMLP-induced neutrophil migration assay); exhibits limited off-target effects in kinome profiling of 154 identified lipid and protein kinases and 922 other proteins.
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CAS Number1159824-67-5
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₁₅H₁₇FN₆O₂S
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Molecular Weight364.4
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Cell PermeableYes
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Purity>98%
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SolubilitiesDMSO
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HandlingProtect from air and light
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Tag LineA selective PI3K-γ inhibitor
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life36 months
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PubChem CID42623951
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SMILESCC(C)(C)NS(=O)(=O)C1=CN=CC(=C1)C2=CN3C(=NC(=N3)N)C(=C2)F
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InChiInChI=1S/C15H17FN6O2S/c1-15(2,3)21-25(23,24)11-4-9(6-18-7-11)10-5-12(16)13-19-14(17)20-22(13)8-10/h4-8,21H,1-3H3,(H2,17,20)
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InChi KeyRXRZPHQBTHQXSV-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Short nameCZC24832
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Alternative nameCZC24832
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