-
Form
liquid
-
Purification
Immunogen affinity purified
-
Purity
≥95% as determined by SDS-PAGE
-
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
-
Background
This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
-
Immunogen
neural precursor cell expressed, developmentally down-regulated 4-like
-
Synonyms
KIAA0439, NEDL3
-
Calculated MW
113 kDa
-
Uniprot ID
Q96PU5
-
Specificity
Human, Mouse, Rat
-
Tested Application
ELISA, WB, IHC
-
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
-
Image1
Immunohistochemistry of paraffin-embedded human prostate cancer using FNab05646(NEDD4L antibody) at dilution of 1:100
-
Image4
K-562 cells were subjected to SDS PAGE followed by western blot with FNab05646(NEDD4L antibody) at dilution of 1:1000
-
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
-
Properties
If you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translation
anticorps
-
Gene target
-
Gene symbol
NEDD4L
-
Short name
anti- NEDD4L antibody
-
Technique
Antibody, anti, antibody to, antibodies against human proteins, antibodies for
-
Host
Rabbit
-
Isotype
IgG
-
Alternative name
antibody to- neural precursor cellular expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase (antibody to-)
-
Alternative technique
antibodies
-
Alternative to gene target
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase, hNEDD4-2 and NEDD4-2 and NEDD4.2 and RSP5, NEDD4L and IDBG-3835 and ENSG00000049759 and 23327, ion channel binding, nuclei, Nedd4l and IDBG-154290 and ENSMUSG00000024589 and 83814, NEDD4L and IDBG-644828 and ENSBTAG00000005412 and 510003
-
