Synonyms Somatomedin C, IGF-I, IGFI, IGF1, IGF-IA, Mechano growth factor, MGF.
Alternates names Somatomedin C, IGF-I, IGFI, IGF1, IGF-IA, Mechano growth factor, MGF.
Taglines An endocrine hormone binding to IGF1R
NCBI Gene ID #. 24482
Gene Source Rat
Accession # P08025
Source E. coli
Activity (Specifications/test method) N/A
Biological activity The ED₅₀ was determined by two methods: 1) By stimulation of protein synthesis in rat L6 myoblasts, the ED₅₀ was found to be
Molecular Weight 7.69 kDa
Storage Temp. -20°C
Shelf Life 1 year
Appearance Lyophilized protein
Handling Centrifuge the vial prior to opening.
Usage For Research Use Only! Not to be used in humans
Description IGF-I, IGF-II, insulin-like growth factors -1 and -2 are important regulators of signaling that mediates growth and metabolism in cells. Insulin-like growth factor -1 shares structural homology with proinsulin and is mainly produced by liver. IGF-1 acts via specific receptor, IGF-1R, a heterodimeric tyrosine kinase receptor that signals to various second messenger pathways such as MAPK, Raf/Ras and PI3K cascades.
About Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
Latin name Rattus norvegicus
Additional source Recombinants or rec. proteins
Gene target -
Short name IGF-I, recombinant
Technique Recombinant, IGF
Alternative name IGF-I, rat recombinant
Alternative technique rec