C-Kit/CD117 Antibody (NT)
-
Catalog number
6777-100
-
Price
Please ask
-
Size
100 μl
-
-
Antibody Target
c-Kit/CD117
-
Target Alternative Name
KIT, Mast/stem cell growth factor receptor, Proto-oncogene tyrosine-protein kinase Kit
-
Antibody Type
Polyclonal
-
Species Reactivities
Human.
-
Immunogen Sequence
This c-KIT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9-40 amino acids from the N-terminal region of human c-KIT.
-
Accession
3815
-
Gene Id
P10721
-
Appearance
Colorless liquid
-
Form
Liquid
-
Formulation
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
-
Application
Western blot, IHC, IF.
-
Positive Control
Western blot: HeLa cell lysate, IHC: Breast carcinoma, FACS: Hela cells.
-
Application And Usages
WB: 1:1000, IHC: 1:10 – 1:50, IF: 1:10 – 1:50.
-
Description
The c-Kit proto-oncogene is a member of the receptor tyrosine kinase family and, more specifically, is closely related to the platelet derived growth factor receptor (PDGFR). c-Kit, the normal cellular homolog of the HZ4-feline sarcoma virus transforming gene (v-Kit), encodes a transmembrane receptor. c-Kit regulates a variety of biological responses including chemotaxis, cell proliferation, apoptosis, and adhesion. c-Kit is also identical with the product of the W locus in mice and, as such, is integral to the development of mast cells and hematopoiesis. The ligand for the c-Kit receptor (KL) has been identified and is encoded at the murine steel (SI) locus. Kit is the human homolog of the proto-oncogene c-Kit. Mutations in Kit are integral for tumor growth and progression in various cancers.
-
Storage Condition
-20 °C
-
Shipping Condition
gel pack
-
Shelf Life
12 months
-
Usage
For Research Use Only! Not to be used in humans.
-
Handling
The antibody solution should be gently mixed before use.
-
Western Blot Verified
Verified
-
Immunocytochemistry Verified
Verified
-
Immunofluorescence Verified
Verified
-
Immunoprecipitation Verified
Not Verified
-
ELISA Verified
Not Verified
-
ChIP Verified
Not Verified
-
Flow Cytometry Verified
Not Verified
-
-
Properties
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translation
anticorps
-
Gene target
-
Gene symbol
KIT
-
Short name
C-Kit/CD117 Antibody (NT)
-
Technique
Antibody, antibodies against human proteins, antibodies for
-
Isotype
Rabbit IgG
-
Alternative name
C-reagent/CD117 (antibody to-) (NT)
-
Alternative technique
antibodies, kits
-
Alternative to gene target
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, C-Kit and CD117 and PBT and SCFR, KIT and IDBG-18980 and ENSG00000157404 and 3815, transferase activity, Extracellular, Kit and IDBG-172083 and ENSMUSG00000005672 and 16590, KIT and IDBG-642326 and ENSBTAG00000002699 and 280832
-
Gene info
MeSH Data
-
Name
-
Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
Similar products
