CD3d Antibody

• Catalog number
  6936-50
• Price
  Please ask
• Size
  50 µl

• Antibody Target
  CD3d
• Target Alternative Name
  T3D; T-cell surface glycoprotein CD3 delta chain; T-cell receptor T3 delta chain; CD3d
• Antibody Type
  Polyclonal
• Species Reactivities
  Human, Monkey
• Immunogen Sequence
  This CD3d antibody is generated from KLH-conjugated synthetic peptide encompassing a sequence within the center region of human CD3d. The exact sequence is proprietary.
• Accession
  P04234
• Gene Id
  915
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  1 mg/ml
• Formulation
  1 mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
• Purification
  Immunogen Affinity chromatography
• Application
  WB, IF/IC
• Positive Control
  WB: CCRFCEM, Jurkat, HuT78 whole cell lysates, IF/IC: Jurkat cells
• Application And Usages
  WB: 1:500 - 1:1000, IF/IC: 1:100 – 1:500
• Description
  T-cell surface glycoprotein CD3 delta chain, also known as CD3D, is a single-pass type I membrane protein. CD3D, together with CD3-gamma,CD3-epsilon and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. This complex is critical for T-cell development and function, and represents one of the most complex transmembrane receptors. The T cell receptor-CD3 complex is unique in having ten cytoplasmic immunoreceptor tyrosine based activation motifs (ITAMs). Defects in CD3D cause severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK cell-positive (T-/B+/NK+SCID) which is a genetically and clinically heterogeneous group of rare congenital disorders characterized by impairment of both humoral and cell-mediated immunity, leukopenia, and low or absent antibody levels.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Verified
• Immunoprecipitation Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Dot Blot Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CD3d  
• Gene symbol
  CD3D
• Short name
  CD3d Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  CD3d molecule, delta (CD3-TCR complex) (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  CD3d molecule, delta (CD3-TCR complex), CD3-DELTA and IMD19 and T3D, CD3D and IDBG-73628 and ENSG00000167286 and 915, protein heterodimerization activity, Plasma membranes, Cd3d and IDBG-159041 and ENSMUSG00000032094 and 12500, CD3D and IDBG-631274 and ENSBTAG00000006452 and 281053

Gene info

• Identity
  HGNC:1673
• Gene
  CD3D
• Long gene name
  CD3d molecule
• Synonyms gene
  • T3D
• Synonyms gene name
  • CD3d antigen, delta polypeptide (TiT3 complex)
  • CD3d molecule, delta (CD3-TCR complex)
• GenBank acession
  • X01451
• Locus
  11q23.3
• Discovery year
  1986-01-01
• Entrez gene record
  915
• RefSeq identity
  • NM_000732
• Classification
  • CD molecules
• VEGA ID
  OTTHUMG00000166970
• Locus Specific Databases
  • CD3Dbase: Mutation registry for Autosomal recessive CD3delta deficiency
  • LRG_37

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

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