DDP-38003 dihydrochloride

• Catalog number
  B1958-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  N-[4-[(1R,2S)-2-aminocyclopropyl]cyclohexyl]-4-(4-methylpiperazin-1-yl)benzamide;dihydrochloride
• Description
  DDP-38003 dihydrochloride is a potent, orally available inhibitor of histone lysine-specific demethylase 1A (KDM1A/LSD1) with an IC₅₀ of 84 nM.
• CAS Number
  1831167-98-6
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₁H₂₈Cl₂N₄O
• Molecular Weight
  423.38
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO
• Handling
  Protect from air and light
• Tag Line
  A potent inhibitor of histone lysine-specific demethylase 1A (KDM1A/LSD1)
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  129627552
• PubChem CID Link
• SMILES
  CN1CCN(CC1)C2=CC=C(C=C2)C(=O)NC3CCC(CC3)C4CC4N.Cl.Cl
• InChi
  InChI=1S/C21H32N4O.2ClH/c1-24-10-12-25(13-11-24)18-8-4-16(5-9-18)21(26)23-17-6-2-15(3-7-17)19-14-20(19)22;;/h4-5,8-9,15,17,19-20H,2-3,6-7,10-14,22H2,1H3,(H,23,26);2*1H/t15?,17?,19-,20+;;/m1../s1
• InChi Key
  HFUZPOURCSSHLY-OAXVCWOXSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  DDP-38003   dihydrochloride  
• Gene symbol
  TIMM8A
• Short name
  DDP-38003 dihydrochloride
• Alternative name
  DDP-38003 dihydrochloride

Gene info

• Identity
  HGNC:11817
• Gene
  TIMM8A
• Long gene name
  translocase of inner mitochondrial membrane 8A
• Synonyms gene
  • DFN1
• Synonyms gene name
  • translocase of inner mitochondrial membrane 8 (yeast) homolog A
  • translocase of inner mitochondrial membrane 8 homolog A (yeast)
• Synonyms
  • DDP
  • MTS
• GenBank acession
  • U66035
• Locus
  Xq22.1
• Discovery year
  1999-12-01
• Entrez gene record
  1678
• Pubmed identfication
  • 10552927
  • 8841189
• RefSeq identity
  • NM_004085
• VEGA ID
  OTTHUMG00000022028

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