PD 153035 Hydrochloride

  • Catalog number
    1656-2
  • Price
    Please ask
  • Size
    2 mg
  • Alternative_name
    N-(3-Bromophenyl)-6,7-dimethoxy-4-quinazolinamine hydrochloride: AG 1517; NSC-669364; SU 5271
  • Description
    An extremely potent and specific inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase (IC₅₀ = 25 pM). Inhibits other purified kinases only at micromolar or higher concentrations.
  • CAS Number
    153436-54-5
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₁₆H₁₄BrN₃O₂.HCl
  • Molecular Weight
    396.67
  • Cell Permeable
    Yes
  • Purity
    ≥95% by HPLC
  • Solubilities
    DMSO (5 mg/ml)
  • Handling
    Protect from air and light
  • Tag Line
    An EGFR inhibitor
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    24 months
  • MDL Number
    MFCD01074805
  • PubChem CID
    11246488
  • SMILES
    COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)Br)OC.Cl
  • InChi
    InChI=1S/C16H14BrN3O2.ClH/c1-21-14-7-12-13(8-15(14)22-2)18-9-19-16(12) 20-11-5-3-4-10(17)6-11;/h3-9H,1-2H3,(H,18,19,20);1H
  • InChi Key
    ZJOKWAWPAPMNIM-UHFFFAOYSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    PD 153035 Hydrochloride
  • Alternative name
    PD 153035 Hydrochloride
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