anti-ARRB2 Antibody

• Catalog number
  30-345
• Price
  Please ask
• Size
  50 ug

• Gene info
  Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. ARRB2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors.Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.
• Gene names
  ARRB2, ARB2, ARR2, DKFZp686L0365, BARR2
• Antibodie s label
  unlabelled serum
• Purity
  Antibody is purified by peptide affinity chromatography method.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Antigen
  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ARRB2.
• Immuno application
  ELISA, Western Blot, immuno-histo-chemistry
• Antibody advice
  ARRB2 antibody can be used for detection of ARRB2 by ELISA at 1:312500. ARRB2 antibody can be used for detection of ARRB2 by western blot at 1.0 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
• Suspention pH azide
  Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
• Keep at
  For short periods of storage (days) store at 4 grades C. For longer periods of storage, store ARRB2 antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.
• Works with
  Human, Dog
• Omim nr
  39812055
• Ncbi nr
  NP_945355
• KDa
  44 kDa, 46 kDa
• Vial with antibody
  Lyophilized
• Quantity per ml
  1 mg/ml
• NCBI GENE nr
  409
• GENE symbol
  ARRB2
• Antigene name
  arrestin, beta 2
• Source
  Homo sapiens
• Protein nr
  A8K4I6
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  ARRB2  
• Gene symbol
  ARRB2
• Short name
  anti-ARRB2 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toARRB2 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  arrestin, beta 2, ARB2 and ARR2 and BARR2, ARRB2 and IDBG-19263 and ENSG00000141480 and 409, 14-3-3 protein binding, nuclei, Arrb2 and IDBG-194248 and ENSMUSG00000060216 and 216869, ARRB2 and IDBG-634360 and ENSBTAG00000035587 and 100851153,281638

Gene info

• Identity
  HGNC:712
• Gene
  ARRB2
• Long gene name
  arrestin beta 2
• Synonyms gene
  • ARR2
• Synonyms gene name
  • arrestin, beta 2
• Synonyms
  • BARR2
  • DKFZp686L0365
• Synonyms name
  • arrestin 3
• Locus
  17p13.2
• Discovery year
  1994-01-10
• Entrez gene record
  409
• Pubmed identfication
  • 7695743
• RefSeq identity
  • NM_004313
• Classification
  • Classical arrestins
• VEGA ID
  OTTHUMG00000090759

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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