SW-033291
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Catalog number9584-25
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PricePlease ask
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Size25 mg
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Alternative_name2-(Butylsulfinyl)-4-phenyl-6-(2-thienyl)-thieno[2,3-b]pyridin-3-amine;SW033291
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DescriptionSW-033291 is a potent inhibitor of 15-hydroxy prostaglandin dehydrogenase (15-PGDH) (Ki = ~0.1 nM). It rapidly increases the levels of PGE2 in bone marrow and other tissues in mice after intraperitoneal injection. SW033291 accelerates hematopoietic recovery in mice receiving bone marrow transplant and promotes tissue regeneration in mouse models of colon and liver injury.
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CAS Number459147-39-8
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₂₁H₂₀N₂OS₃
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Molecular Weight412.58
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO (>25 mg/ml)
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HandlingProtect from air and light
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Tag LineA potent 15-PGDH (15-hydroxy prostaglandin dehydrogenase) inhibitor
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life36 months
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PubChem CID3337839
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SMILESCCCCS(=O)C1=C(C2=C(S1)N=C(C=C2C3=CC=CC=C3)C4=CC=CS4)N
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InChiInChI=1S/C21H20N2OS3/c1-2-3-12-27(24)21-19(22)18-15(14-8-5-4-6-9-14)13-16(23-20(18)26-21)17-10-7-11-25-17/h4-11,13H,2-3,12,22H2,1H3
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InChi KeyLCYAYKSMOVLVRL-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Gene symbolTUBB, MEX3D, SLC4A1, CDK5RAP3
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Short nameSW-033291
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Alternative nameSW-033291
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Gene info
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Identity
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Gene
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Long gene nametubulin beta class I
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Synonyms gene name
- tubulin, beta polypeptide
- tubulin, beta
- tubulin, beta class I
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2004-11-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Tubulins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemex-3 RNA binding family member D
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Synonyms gene
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Synonyms gene name
- ring finger and KH domain containing 1
- mex-3 homolog D (C. elegans)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2004-03-17
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Ring finger proteins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namesolute carrier family 4 member 1 (Diego blood group)
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Synonyms gene
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Synonyms gene name
- Waldner blood group
- erythrocyte membrane protein band 3
- Diego blood group
- solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group)
- solute carrier family 4 (anion exchanger), member 1
- solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
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Synonyms
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Synonyms name
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Locus
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Discovery year1988-04-20
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Blood group antigens
- Solute carriers
- CD molecules
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameCDK5 regulatory subunit associated protein 3
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2002-07-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID