MDM4 ANTIBODY, ALEXA FLUOR 647
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Catalog number
bs-7663R-A647
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Price
Please ask
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Size
100ul
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Long name
MDM4 POLYCLONAL ANTIBODY, ALEXA FLUOR 647 Conjugated
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Also known as
Anti-MDM4 PAb ALEXA FLUOR 647
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Category
Conjugated Primary Antibodies
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Conjugated with
ALEXA FLUOR® 647
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Host Organism
Rabbit (Oryctolagus cuniculus)
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Target Antigen
MDM4
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Specificity
This is a highly specific antibody against MDM4.
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Modification
Unmodified
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Modification Site
None
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Clonality
Polyclonal
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Clone
Polyclonal antibody
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Concentration
1ug per 1ul
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Immunogen range
300-330/490
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Subcellular location
Nucleus
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Source
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MDM4
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Gene ID Number
4194
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Swiss Prot
O15151
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Tested applications
IF(IHC-P)
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Recommended dilutions
IF(IHC-P)(1:50-200)
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Crossreactivity
Human, Mouse, Rat
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Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the antigen
Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions.
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Purification
Purified by Protein A.
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Storage conditions
Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
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Excitation emission
650nm/665nm
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Synonyms
HDMX; MDMX; MRP1; Protein Mdm4; Double minute 4 protein; Mdm2-like p53-binding protein; Protein Mdmx; p53-binding protein Mdm4; MDM4
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Properties
For facs or microscopy Alexa 1 conjugate. Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-MDM4 exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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Conjugation
Alexa Fluor, ALEXA FLUOR 647
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French translation
anticorps
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Gene target
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Gene symbol
MDM4
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Short name
Anti-MDM4
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Technique
Antibody, antibodies against human proteins, antibodies for
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Isotype
Immunoglobulin G (IgG)
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Label
ALEXA FLUOR 647
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Alternative name
MDM4 POLYCLONAL ANTIBODY, ALEXA FLUOR 647
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Alternative technique
antibodies
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Alternative to gene target
Mdm4 p53 binding protein homolog (mouse), HDMX and MDMX and MRP1, MDM4 and IDBG-106054 and ENSG00000198625 and 4194, enzyme binding, nuclei, Mdm4 and IDBG-192393 and ENSMUSG00000054387 and 102641776,17248, BT.36413 and IDBG-628663 and ENSBTAG00000006255 and 100138492,514225
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Gene info
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Identity
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Gene
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Long gene name
MDM4 regulator of p53
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Synonyms gene name
- mouse double minute 4, human homolog of; p53-binding protein
- Mdm4, transformed 3T3 cell double minute 4, p53 binding protein (mouse)
- Mdm4 p53 binding protein homolog (mouse)
- MDM4, p53 regulator
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Synonyms
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GenBank acession
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Locus
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Discovery year
1997-09-05
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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