Caspase 10 Antibody

Applications

WB IHC IF ELISA
Source

Rabbit
Reactivity

H
MW kDa

58 kDa
Target Modification

Unmodified/Total
Immunogen

The antiserum was produced against synthesized peptide derived from human Caspase 10.
Immunogen Range

430-479
Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.
Specificity

Caspase 10 Antibody detects endogenous levels of total Caspase 10 protein.
Gene ID

843
Swiss Prot No

Q92851-2/4
OMIM No

601762
Unigene No

Hs.5353
NCBI Gene Symbol

CASP10
Synonyms

ALPS2; apoptotic protease Mch-4; CASP-10; CASPA; caspase-10; FADD-like ICE2; FAS-associated death domain protein interleukin-1B-convert
Storage Stability

Stable at -20°C for at least 1 year.
Physical Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Clonality

Polyclonal
Concentration

1 mg/ml
Properties

If you buy Antibodies supplied by Assay Biotech they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Description

Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
French translation

anticorps

Identity

HGNC:16422
Gene

CARD10
Long gene name

caspase recruitment domain family member 10
Synonyms gene name
- caspase recruitment domain family, member 10
Synonyms
- CARMA3
- BIMP1
GenBank acession
- AF086324
Locus

22q13.1
Discovery year

2002-09-19
Entrez gene record

29775
Pubmed identfication
- 11259443
- 11356195
RefSeq identity
- NM_014550
Classification
- Membrane associated guanylate kinases
- Caspase recruitment domain containing
VEGA ID

OTTHUMG00000150592

Identity

HGNC:1500
Gene

CASP10
Long gene name

caspase 10
Synonyms gene name
- caspase 10, apoptosis-related cysteine protease
- caspase 10, apoptosis-related cysteine peptidase
Synonyms
- MCH4
- FLICE-2
Synonyms name
- FAS-associated death domain protein interleukin-1B-converting enzyme 2
GenBank acession
- U60519
Locus

2q33.1
Discovery year

1997-04-21
Entrez gene record

843
Pubmed identfication
- 8755496
RefSeq identity
- NM_032977
Classification
- Caspases
- Death effector domain containing
- Death inducing signaling complex
VEGA ID

OTTHUMG00000132818
Locus Specific Databases
- CASP10base: Mutation registry for Autoimmune lymphoproliferative syndrome, type II (ALPS2)
- LRG_33

Identity

HGNC:24821
Gene

RFFL
Long gene name

ring finger and FYVE like domain containing E3 ubiquitin protein ligase
Synonyms gene name
- ring finger and FYVE-like domain containing
Synonyms
- rififylin
- fring
- RNF189
- RNF34L
- CARP2
- CARP-2
Synonyms name
- caspase 8 and 10 associated RING protein-2
GenBank acession
- AF434816
Locus

17q12
Discovery year

2005-08-16
Entrez gene record

117584
Pubmed identfication
- 15229288
RefSeq identity
- NM_057178
Classification
- Ring finger proteins
VEGA ID

OTTHUMG00000132933

Name

Blotting, Western
Concept

Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data